6533b86cfe1ef96bd12c8bba
RESEARCH PRODUCT
The fine structure of de-and reinnervated muscle spindles
J. Michael SchröderJ. Michael SchröderJ. Michael Schrödersubject
Nerve CrushMuscle spindleMotor nerveSensory systemBasement MembranePathology and Forensic Medicinelaw.inventionCellular and Molecular NeuroscienceMuscle pathologyMyofibrilslawmedicineAnimalsMuscle SpindlesMotor NeuronsMuscle DenervationChemistryAnatomySciatic NerveAxonsMuscle DenervationNerve RegenerationRatsMicroscopy ElectronIntercellular Junctionsmedicine.anatomical_structureFemaleSchwann CellsNeurology (clinical)Sciatic nerveElectron microscopeWallerian Degenerationdescription
Reinnervated muscle spindles in lower lumbrical muscles of rats studied 17 days to 24 months after crushing the sciatic nerve showed a series of alterations which have not been analysed, thus far, by electron microscopy. There was a striking increase of the number of intrafusal muscle fibers seen in approximately 20% of reinnervated spindles. These spindles showed 5–11 intrafusal muscle fibers whereas normal spindles usually contained 3–4 fibers only.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1974-01-01 | Acta Neuropathologica |