6533b86dfe1ef96bd12c93cf

RESEARCH PRODUCT

Response to Comment on “Characterizing the N-Terminal Processing Motif of MHC Class I Ligands”

Hansjörg SchildStefan Tenzer

subject

chemistry.chemical_classificationSignal peptideN-terminusBiochemistrybiologychemistryImmunologyMHC class IImmunologybiology.proteinImmunology and AllergyLimitingAmino acid

description

The possibility that ERAAP plays a role in limiting the presentation of peptides derived from signal peptides may be tempting from an immunologist’s view. In eukaryotic cells, signal peptides have a mean length of 22 amino acids and are removed by signal peptide peptidases from the N terminus of

https://doi.org/10.4049/jimmunol.181.6.3731-a