6533b86dfe1ef96bd12c9d6b

RESEARCH PRODUCT

Pyrrole Studies. Part 40.1Synthesis of 2- and 3-Substitoted 1-Methylindoles from Vinylpyrroles.

Eugenia Gonzalez-rosendeElena Zaballos-garcíaJosé Sepúlveda-arquesR. A. Jones

subject

chemistry.chemical_compoundChemistryYield (chemistry)Organic ChemistryOrganic chemistryDehydrogenationPyrrole

description

Abstract 4-Substituted-2-vinylpyrroles are more reactive than 2-substituted-4-vinylpyrroles in their reaction with DMAD to yield, respectively, 6/7- and 4,5-dihydroindoles, which are readily dehydrogenated to give indoles possessing electron-withdrawing substitutents at the 3- and 2-positions.

https://doi.org/10.1080/00397918808081328