6533b86dfe1ef96bd12ca090

RESEARCH PRODUCT

Ovulation-inducing activity of luliberin (LHRH) complexed by copper(II), nickel(II), and zinc(II) ions.

Elzbieta MasiukiewiczHenryk KozlowskiAnna Walczewska-sumorokElż̇bieta PotargowiczBarbara Rzeszotarska

subject

Ovulationendocrine systemmedicine.medical_specialtymedia_common.quotation_subjectMolecular Sequence Datachemistry.chemical_elementZincGonadotropin-releasing hormonePeptide hormoneBiochemistryInorganic ChemistryMetalGonadotropin-Releasing HormoneOvulation InductionNickelInternal medicinemedicineAnimalsAmino Acid SequenceRats Inbred BUFOvulationmedia_commonRats Inbred StrainsCopperRatsZincEndocrinologychemistryvisual_artvisual_art.visual_art_mediumFemaleLuteinizing hormoneCopperNuclear chemistryHormone

description

We have shown that the complexation of luteinizing hormone releasing hormone, luliberin (LHRH), a hypothalamic neurohormone, by Cu(II), Ni(II), and Zn(II) may affect its basic, ovulation-inducing potency in the dose responsive manner. Some explanation of the obtained results are offered here.

10.1016/0162-0134(90)80045-yhttps://pubmed.ncbi.nlm.nih.gov/2092076