6533b86dfe1ef96bd12ca861

RESEARCH PRODUCT

Multicommutation as a powerful new analytical tool

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description

This review presents the state of the art of the emerging continuous-flow methodology based on solenoid valves. This uses flow networks to deliver sample and reagent solutions by controlling the time of flow through the ON/OFF modes of solenoid valves and takes advantage of existing flow injection analysis (FIA) or sequential injection analysis (SIA) device or manifold configurations. It allows one to insert a single plug of sample (or reagent) into the carrier or carrier-reagent stream, mimicking the approaches of FIA or SIA. In addition to the modes used in FIA and SIA, the methodology provides a different mode, based on delivery of a series of alternating sequential insertions of very small volumes of sample and reagent. This gives rise to different hydrodynamic and chemical processes and new analytical potential. The fundamentals of the methodology are discussed together with a broad view and critical survey of the advantages and the possible trends.