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RESEARCH PRODUCT
ChemInform Abstract: Low-Loading Asymmetric Organocatalysis
Francesco GiacalonePaola AgrigentoMichelangelo GruttadauriaRenato Notosubject
chemistry.chemical_compoundchemistryOrganocatalysisEnantioselective synthesisPillarGeneral MedicineLewis acids and basesBrønsted–Lowry acid–base theoryCarbeneCombinatorial chemistryCatalysisdescription
Asymmetric organocatalysis is now recognized as the third pillar of asymmetric synthesis. Recent years have witnessed increasing interest towards the use of highly active and stereoselective organocatalysts. This critical review documents the advances in the development of chiral organocatalysts which are systematically used in ≤3 mol% loading in all the sub-areas of the field, namely aminocatalysis, Bronsted acids and bases, Lewis acids and bases, hydrogen bond-mediated catalysis, phase transfer and N-heterocyclic carbene catalyses (194 references).
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-05-25 | ChemInform |