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RESEARCH PRODUCT

Advance on Resveratrol Application in Bone Regeneration: Progress and Perspectives for Use in Oral and Maxillofacial Surgery

Viviana De CaroRodolfo MauceriGiuseppina CampisiDenise Murgia

subject

0301 basic medicinealveolar bone lossBone Regenerationmedicine.medical_treatmentlcsh:QR1-502ReviewResveratrolBioinformaticsBone tissueBiochemistrylcsh:Microbiology03 medical and health scienceschemistry.chemical_compoundresveratrol scaffold0302 clinical medicineIn vivoSettore MED/28 - Malattie OdontostomatologicheAnimalsHumansMedicineBone regenerationMolecular Biologybone-regenerationbone defectbusiness.industryRegeneration (biology)alveolar bone locraniofacial tissue030206 dentistryBone defectSurgery Oral030104 developmental biologymedicine.anatomical_structurechemistryResveratrolSettore CHIM/09 - Farmaceutico Tecnologico ApplicativoChronic DiseaseOral and maxillofacial surgerybusinessAdjuvant

description

The natural polyphenol Resveratrol (RSV) claims numerous positive effects on health due to the well documented biological effects demonstrating its potential as a disease-preventing agent and as adjuvant for treatment of a wide variety of chronic diseases. Since several studies, both in vitro and in vivo, have highlighted the protective bone aptitude of RSV both as promoter of osteoblasts’ proliferation and antagonist of osteoclasts’ differentiation, they could be interesting in view of applications in the field of dentistry and maxillofacial surgery. This review has brought together experimental findings on the use of RSV in the regeneration of bone tissue comprising also its application associated with scaffolds and non-transfusional hemocomponents.

yearjournalcountryeditionlanguage
2019-01-09
10.3390/biom9030094http://hdl.handle.net/10447/346776