6533b86efe1ef96bd12cbc0c

RESEARCH PRODUCT

New macrolactones from the defensive salivary secretion of soldiers of the african termite Pseudacanthotermes spiniger

Valérie PlasmanSophie ConnétableAlain RobertChristian BordereauDésiré DalozeJean Claude Braekman

subject

chemistry.chemical_classificationSalivary secretionChemistryOrganic ChemistryDrug DiscoverySecretionPseudacanthotermes spinigerPolysaccharideBiochemistryMicrobiology

description

The salivary defensive secretion of large soldier termites of the species Pseudacanthotermes spiniger contains two novel macrocyclic lactones [22-keto-hexacosanolide (2) and 2-hydroxy-24-keto-octacosanolide (3)] together with the already known macrolactone hexacosanolide (1). In addition, the secretion contains important amounts of a polysaccharide based mainly upon β-glucopyranose, β-glucosamine and N-acetyl-β-glucosamine in equal amount.

https://doi.org/10.1016/s0040-4039(99)01961-9