6533b86efe1ef96bd12cbc3f

RESEARCH PRODUCT

The TH1 Lymphokine Interferon-γ is a Potent Upregulator of Dendritic Cells with Phagocytic Capacity in GM-CSF Supplemented Bone Marrow Cultures

Vera HofMichael RobbersChristoph ScheicherKonrad ReskeHeike Corban

subject

Tissue culturemedicine.anatomical_structureMyeloidChemistryCellImmunologymedicineLymphokineDendritic cellBone marrowMolecular biologyPhenotypeIn vitro

description

Myeloid dendritic cells (DC), macrophages and granulocytes are descendants of a hematopoietic progenitor cell that originates in the bone marrow1. Thus, bone marrow derived cells distributed in tissue culture in the presence of GM-CSF give rise to the three leukocyte populations which under various in vitro culture conditions proceed in differentiation and phenotypic maturation2–7.

https://doi.org/10.1007/978-1-4757-9966-8_37