6533b86efe1ef96bd12cbd6e
RESEARCH PRODUCT
Polycondensed nitrogen heterocycles. X. 5,6,7,8-Tetrahydropyrrolo[1,2-e][1,5]benzodiazocin-7-ones. A new ring system
Isabella D'asdiaAnna Maria AlmericoGaetano DattoloEnrico AielloGirolamo Cirrincionesubject
chemistry.chemical_compoundchemistryOrganic ChemistryCondensationOrganic chemistrychemistry.chemical_elementRing (chemistry)TolueneNitrogenCatalysisPalladiumdescription
The synthesis of a new heterocyclic ring system is described. Condensation of 1,4-diketones 1a,b with β-alanine gave the substituted propionic acids 2a,b which upon reduction with palladium on charcoal afforded compounds 3a,b. Title compounds 4a,b were obtained by refluxing 3a,b in toluene with p-toluenesulphonic acid as catalyst.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1981-10-01 | Journal of Heterocyclic Chemistry |