6533b86ffe1ef96bd12cd1a2
RESEARCH PRODUCT
4-[3-(4-Fluorophenyl)-5-isopropylisoxazol-4-yl]pyridine
Christian PeiferMohammed AbadlehDieter SchollmeyerStefan Laufersubject
chemistry.chemical_compoundMolecular geometryChemistryPyridineGeneral Materials ScienceGeneral ChemistryIsoxazoleCondensed Matter PhysicsRing (chemistry)Medicinal chemistrydescription
The molecular structure of the title compound, C17H15FN2O, was determined in the course of our studies on mitogen-activated protein kinase inhibitors. The exocyclic bond angles at the carbon atoms of the isoxazole ring bearing the pyridyl and 4-fluorophenyl rings are 130.0 (2) and 129.2 (2)°, respectively. The pyridine and 4-fluorophenyl rings are twisted relative to the isoxazole ring by 80.2 (2) and 19.1 (1)°, respectively.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2006-08-09 | Acta Crystallographica Section E Structure Reports Online |