6533b86ffe1ef96bd12cd358

RESEARCH PRODUCT

Allele frequencies distribution of 16 forensic STR loci in a Western Sicilian population sample

Argo ASalvatore ProcacciantiStefania ZerboCristina MondelloAlessio AsmundoSimona MarrettaElvira Ventura Spagnolo

subject

0301 basic medicineDNA databaseHealth (social science)Population sampleConcordance2734BiologyStrPathology and Forensic MedicineAllele frequenciePowerPlexLoss of heterozygosity03 medical and health sciencesSettore MED/43 - Medicina LegaleItalian populationlcsh:Law in general. Comparative and uniform law. JurisprudenceGenotypingAllele frequencyGeneticslcsh:R5-920Allele frequencies; DNA database; Italian population; PowerPlex; Str; 2734; Health (social science); LawAllele frequencieslanguage.human_languageForensic science030104 developmental biologylcsh:K1-7720Str locilanguagelcsh:Medicine (General)SicilianLaw

description

Abstract The PowerPlex® ESI 17 Fast and ESX 17 Fast Systems represent faster cycling versions released by Promega® to follow the requirements of ENFSI and EDNAP groups’ for new STR genotyping systems in Europe. Allele frequencies and forensic parameters were estimated in a population sample of 120 unrelated healthy individuals living in Sicily (Western Sicilian population sample) using PowerPlex® ESI 17 Fast and PowerPlex® 17 Fast Systems. Full concordance of the results for both systems was observed. No significant deviation from Hardy-Weinberg equilibrium was detected. The observed heterozygosity changed from 0.85833 for FGA to 0.95 for TH01. The combined power of discrimination for the 16 loci was >0.999999.

yearjournalcountryeditionlanguage
2017-01-01
10.1186/s41935-017-0013-yhttp://hdl.handle.net/11570/3134452