6533b86ffe1ef96bd12cd452

RESEARCH PRODUCT

Glycosidopyrroles. Part 4. 1-β-D-ribofuranosyl-pyrroles and indoles as potential antiviral agents

GirolamocirrincionePatrizia DianaGaetano DattoloPaola BarrajaAntonino LauriaAnna Maria Almerico

subject

lcsh:QD241-441lcsh:Organic chemistryChemistryStereochemistryBioactive moleculesOrganic ChemistryCombinatorial chemistry

description

The preparation of new 1-β-D-ribofuranosylpyrroles of type 8 and a new method of synthesis of 1-β-D-ribofuranosylindoles of type 10, according to the scheme, is reported. All these new derivatives showed promising chemical and physical analogies with bioactive molecules but did not show any antiviral activity againstHIV1.

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