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RESEARCH PRODUCT
Molecular Evolution of Defense Pathways in Sponges: Self–Self-recognition and Fight against the Nonself
Johan GardèresXiaohong WangWerner E.g. Müllersubject
SpongeInnate immune systemImmune systembiologyEvolutionary biologyImmunityPhylogeneticsMolecular evolutionSelf recognitionAcquired immune systembiology.organism_classificationMicrobiologydescription
This article provides an overview of the immune system in poriferans at a tissue, cellular, and molecular level. Despite their simple organization, sponges have developed molecular mechanisms to recognize and resist foreign organisms. They are able to distinguish among food organisms, pathogens, and sponge-associated organisms. Although they lack specialized immune cells, sponges display molecular precursors, which are similar to molecular mediators involved in innate and adaptive immune systems, present in more evolutionarily advanced taxa, as outlined in succeeding articles in the Phylogeny section.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-01-01 |