6533b86ffe1ef96bd12cdc6e
RESEARCH PRODUCT
New route to herbertanes via a Suzuki cross-coupling reaction: synthesis of herbertenediol
Antonio AbadConsuelo AgullóDiego JimenezRemedios H. PerniAna C. Cuñatsubject
Terpenechemistry.chemical_compoundchemistryGroup (periodic table)StereochemistryOrganic ChemistryDrug DiscoverySesquiterpeneBiochemistryHerbertenediolCombinatorial chemistryCoupling reactiondescription
Abstract The synthesis of herbertenediol, a relevant member of the herbertane-type sesquiterpene family, is described. The synthesis is based on a new general approach to this group of sesquiterpenes where the herbertane skeleton is constructed using a Suzuki cross-coupling reaction and a [2,3]-sigmatropic Still–Wittig rearrangement as key synthetic steps.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2001-11-01 | Tetrahedron |