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RESEARCH PRODUCT
A survey on features of allergic rhinitis in children
A ZicariL IndinnimeoG De CastroC IncorvaiaF FratiI Dell'albaniP PuccinelliM ScolariM DuseK AhmadC AlessandriE AnastasioE BaldoS BarberiR BernardiniA BoccafogliA BonerL BrunettiC CaffarelliG CapocasaleL CapraM CarboneC CavaliereC CelaniR CervoneA Cesoni MarcelliL ChiniG CortelliniM CostantinoR CutreraI Dello IaconoV De VittoriG DinellaS EspositoE FerrariniF FerraroM GelardiL GualtieroS La GruttaD LiettiV LollobrigidaM MarinoniG MarsegliaS MasieriD MinasiM Del GiudiceV MoscheseL NespoliE NovembreF OccasiM PaceG PajnoM PatriaD PeroniG RicciL RicciardiC RoncalloF SantamariaA SantucciA SciaccaG ScalaG TaddeoG TancrediM ToscaA VarricchioS Zampognasubject
QuestionnairesMalePediatricsmedicine.disease_causeAdrenal Cortex HormoneAllergic rhinitisDrug treatmentAllergenAdrenal Cortex HormonesGrass pollenSurveys and QuestionnairesChildRhinitisAllergen immunotherapybiologyMedicine (all)PyroglyphidaeGeneral MedicineDust mitesResponse to treatmentPhenotypesPhenotypeItalyChild PreschoolFemaleAdolescent; Adrenal Cortex Hormones; Animals; Child; Child Preschool; Female; Histamine Antagonists; Humans; Italy; Male; Rhinitis Allergic Seasonal; Pyroglyphidae; QuestionnairesHistamine AntagonistHumanallergen immunotherapy; phenotypes; aria classification; allergic rhinitis; drug treatmentmedicine.medical_specialtyAllergen immunotherapyAdolescentHistamine AntagonistsAnimals; Questionnaires; Humans; Pyroglyphidae; Child; Italy; Adrenal Cortex Hormones; Child Preschool; Histamine Antagonists; Rhinitis Allergic Seasonal; Adolescent; Female; MaleAllergen immunotherapy; Allergic rhinitis; ARIA classification; Drug treatment; PhenotypesAllergicmedicineAllergic rhinitiAnimalsHumansPreschoolSettore MED/38 - Pediatria Generale e SpecialisticaSeasonalbusiness.industryAnimalQuestionnairePyroglyphidaeRhinitis Allergic Seasonalbiology.organism_classificationDermatologyClinical trialMulticenter studyARIA classificationbusinessdescription
Objective: A number of epidemiologic studies evaluated the prevalence of allergic rhinitis (AR), but few data are available on its different clinical presentations. We addressed this survey to assess the features of AR in children and adolescents. Methods: Thirty-five centers in Italy included 2623 pediatric patients with rhinitis, of whom 2319 suffered from AR, while 304 had other kinds of rhinitis. For each patient a standardized questionnaire was filled in, including ARIA classification, the duration of symptoms, the allergen identified as clinically relevant, the co-morbidities, the kind of treatment, the response to treatment, the satisfaction with the treatment, and the feasibility of allergen immunotherapy (AIT). Results: Of the 2319 patients, 597 (25.7%) had mild intermittent, 701 (30.2%) mild persistent, 174 (7.5%) moderate-severe intermittent, and 773 (33.3%) moderate-severe persistent AR. The allergens most relevant were grass pollen and dust mites. The most frequently used drugs were oral antihistamines (83.1%) and topical corticosteroids (63.5%). The response to treatment was judged as excellent in 13.5%, good in 45.1%, fair in 30.8%, poor in 10%, and very bad in 0.6% of cases. The satisfaction with treatment was judged as very satisfactory in 15.2%, satisfactory in 61.8%, unsatisfactory in 22.4%, and very unsatisfactory in 0.5% of cases. AIT was considered indicated in 53.1% of patients with mild intermittent, 79.2% of moderate-severe intermittent, 72.6% of mild persistent, and 82.7% of moderate-severe persistent AR. Conclusions: The limitation of this study is that the population was not unselected and this prevents epidemiological significance. These results offer confirmation of the adequacy of ARIA guidelines in classifying patients with AR and of the association of severe phenotype with lack of success of drug treatment. © 2013 Informa UK Ltd All rights reserved.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2013-01-01 |