6533b86ffe1ef96bd12ce61d

RESEARCH PRODUCT

Zirconia nanocrystals as submicron level biological label

Marita GavareJanis LiepinsA PatmalnieksD. JankovicaKrisjanis SmitsA Gruduls

subject

Materials scienceNanocrystalbiologyDopingNanotechnologyLuminescence spectraCubic zirconiaLuminescencebiology.organism_classificationSaccharomycesYeast

description

Inorganic nanocrystals are of increasing interest for their usage in biology and pharmacology research. Our interest was to justify ZrO2 nanocrystal usage as submicron level biological label in baker's yeast Saccharomyces cerevisia culture. For the first time (to our knowledge) images with sub micro up-conversion luminescent particles in biologic media were made. A set of undoped as well as Er and Yb doped ZrO2 samples at different concentrations were prepared by sol-gel method. The up-conversion luminescence for free standing and for nanocrystals with baker's yeast cells was studied and the differences in up-conversion luminescence spectra were analyzed. In vivo toxic effects of ZrO2 nanocrystals were tested by co-cultivation with baker's yeast.

yearjournalcountryeditionlanguage
2012-08-20IOP Conference Series: Materials Science and Engineering
https://doi.org/10.1088/1757-899x/38/1/012050