Reactions of 1-isopropyl-3-methyl- and 2,3-dimethylindoles with triethyl orthoformate: New trisindolylmethanes

6533b86ffe1ef96bd12ce657

RESEARCH PRODUCT

Reactions of 1-isopropyl-3-methyl- and 2,3-dimethylindoles with triethyl orthoformate: New trisindolylmethanes

subject

Steric effects chemistry.chemical_compound chemistry Bicyclic molecule Organic Chemistry Structural isomer Organic chemistry Orthoester Nuclear magnetic resonance spectroscopy Triethyl orthoformate Isopropyl

description

Indoles 1 and 2 react with triethyl orthoformate under proton–catalyzed conditions to form trisindolylmethanes. The regioisomer distribution of the products is controlled by steric and electronic factors.

year	journal	country	edition	language
1987-01-01	Journal of Heterocyclic Chemistry

https://doi.org/10.1002/jhet.5570240156

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