6533b870fe1ef96bd12cefc2

RESEARCH PRODUCT

Relationship between ligand conformations and complexation properties in ditopic biphenyl thioureas

Salvador GilPablo GaviñaGemma M. Rodríguez-muñizAna M. Costero

subject

Biphenylchemistry.chemical_compoundThioureaChemistryStereochemistryLigandOrganic ChemistryDrug DiscoveryPolymer chemistryCarboxylateBiochemistryEquilibrium constantStoichiometry

description

Four new homoditopic biphenyl thiourea derivatives have been prepared to be used in carboxylate sensing. Experiments carried out with these ligands have demonstrated that the conformation of the free ligand has a strong influence on both complex stoichiometry and geometry. High equilibrium constants were obtained in DMSO.

yearjournalcountryeditionlanguage
2007-08-01Tetrahedron
https://doi.org/10.1016/j.tet.2007.05.082