6533b870fe1ef96bd12cf067

RESEARCH PRODUCT

ChemInform Abstract: Reductive Cleavage of 2,2,2-Trichloroethyl Esters with Sodium Telluride.

José R. PedroBegoña GarcíaGonzalo BlayC. L. GarciaLuz Cardona

subject

Reaction conditionschemistry.chemical_compoundchemistryReductive cleavagePolymer chemistrySodium tellurideDimethylformamideGeneral Medicine

description

Abstract Carboxylic acids are regenerated from their 2,2,2-trichloroethyl esters by treatment with sodium telluride in dimethylformamide in smooth conditions and with good yields. The reaction conditions are compatible with other functional and protective groups such as methyl ester, acetate or tert-butyldimethylsilyl ethers.

https://doi.org/10.1002/chin.199834072