6533b870fe1ef96bd12cf18c

RESEARCH PRODUCT

Biofilm development by clinical strains of non-pigmented rapidly growing mycobacteria

Ignacio GadeaGuillermo AyalaD. García-almeidaAngel CeldránN.z. Martín-de-hijasJaime EstebanR. Fernández-roblasEnrique Gómez-barrena

subject

Microbiology (medical)Mycobacterium InfectionsbiologyBiofilmclinical significanceBiofilmMotilityGeneral MedicineMycobacterium InfectionsPigments Biologicalbiochemical phenomena metabolism and nutritionbiology.organism_classificationIn vitroMicrobiologyMycobacteriumInfectious DiseasesmotilityBiofilmsrapidly growing mycobacteriaHumansClinical significancemicrotitreBacteriaLocomotionMycobacterium

description

AbstractThe relationship between clinical significance of non-pigmented, rapidly growing mycobacteria (NPRGM), in vitro biofilm development and sliding motility was evaluated in this study. One hundred and sixty-eight clinical strains of NPRGM were included. Forty-one of these were clinically significant isolates. Biofilm was formed by 123 strains. Seventy-six biofilm-positive and 25 biofilm-negative strains showed sliding motility. There was a relationship between clinical significance and biofilm development (p <0.000 001), sliding motility (p 0.0037) and species (p <0.000 001). No relationship was found between motility and biofilm development. The ability to develop biofilm is a characteristic that can have importance in the development of infections caused by NPRGM.

10.1111/j.1469-0691.2009.02882.xhttp://dx.doi.org/10.1111/j.1469-0691.2009.02882.x