6533b870fe1ef96bd12cf397

RESEARCH PRODUCT

Synthesis of Fluorinated and Non-Fluorinated Bicyclic Amidines through Ring-Closing Metathesis

Judit OliverSonia FloresSantos FusteroAna C. Cuñat

subject

Bicyclic moleculeNitrogen heterocyclesOrganic ChemistryAmidineschemistry.chemical_elementMetathesisFluorineMetathesisRing-closing metathesischemistrySalt metathesis reactionFluorineOrganic chemistryPhysical and Theoretical ChemistryAcyclic diene metathesis

description

[EN] An efficient method for the synthesis of fluorinated and non-fluorinated imidazoazepines by a ring-closing metathesis reaction as the key step is described. The influence of the fluorine atoms on the preparation of these bicyclic systems is also studied.

10.1002/ejoc.201101091https://doi.org/10.1002/ejoc.201101091