Mycobacterium tuberculosis rezistence pret antibakteriāliem preparātiem

6533b870fe1ef96bd12cf55b

RESEARCH PRODUCT

Mycobacterium tuberculosis rezistence pret antibakteriāliem preparātiem

Euģēnija Banionite

subject

Zāļu jutības testi antibakteriālā rezistence M. tuberculosis Farmācija tuberkuloze

description

Tuberkuloze ir viens no vadošajiem nāves cēloņiem pasaulē. Par tuberkulozes izraisītāju uzskata M. tuberculosis. Praktiskajā daļā tiek veikti Zāļu jutības testi (ZJT) uz Lēvenšteina-Jensena barotnēm ar M. tuberculosis celmiem, lai noteiktu to rezistenci, kā arī tika apstrādāti rezultāti, kas bija iegūti un apkopoti SIA „RAKUS” Tuberkulozes un plaušu slimību centra Mikobakterioloģijas laboratorijas informācijas sistēmā(LIS). Statistikas analīzē tiek pierādīts, ka pasaulē un Latvijā saslimstības ar tuberkulozes gadījumu skaits samazinās un, savukārt, izārstēto cilvēku skaits paaugstinās. Starp visiem rezistentiem gadījumiem visbiežāk rezistence bija pret pirazinamīdu un izoniazīdu no pirmās rindas medikamentiem un pret etionamīdu no otrās rindas prettuberkulozes medikamentiem. Pret bedahilīnu un linezolīdu nebija rezistentu M. tuberculosis izolātu, bet pret delamanīdu bija konstatēts tikai viens rezistences gadījums 2017. gadā.

year	journal	country	edition	language
2018-01-01

https://dspace.lu.lv/dspace/handle/7/40276

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