6533b870fe1ef96bd12cfc56
RESEARCH PRODUCT
Mimonoside D: a new triterpenoid saponin from Mimosa diplotricha Sauvalle (Fabaceae)
Blondelle Matio KemkuignouJonas KühlbornTill OpatzBeaudelaire Kemvoufo PonouRémy Bertrand TeponnoLéon Azefack TapondjouJean Paul DzoyemClaudie Fokou KenmogneRoland T. Tchuenguemsubject
chemistry.chemical_classificationbiologyOrganic ChemistryVitexinPlant ScienceFabaceaebiology.organism_classificationBiochemistryProteus mirabilisAnalytical Chemistrychemistry.chemical_compoundchemistryBetulinic acidKaempferolMimosa diplotrichaLupeolNuclear chemistryTriterpenoid saponindescription
A new triterpenoid saponin (Mimonoside D: 3-O-��-L-arabinopyranosyl-3��-hydroxyolean-12-en-28-oic acid 28-O-��-D-xylopyranosyl-(1���2)-��-D- glucopyranoside ester (1)) was isolated from the aerial parts of Mimosa diplotricha Sauvalle together with nine known compounds: 7,4���-dihydroxyflavone (2), kaempferol (3), lupeol (4), betulinic acid (5), ��-sitosterol (6), ��-sitosterol-3-O-��-D-glucopyranoside (7), lutein (8), 5,2���-dihydroxy-7,4���,5���-trimethoxyflavone (9) and vitexin (10). Their structures were elucidated on the basis of spectroscopic (1 D and 2 D nuclear magnetic resonance) and high-resolution mass spectrometric data as well as by comparison of their spectral data with those of related compounds. Compounds 2, 7 and 8 had already been isolated from M. diplotricha, while compounds 3, 4, 5 and 6 have been isolated from other Mimosa species. Compound 2 moderately inhibited Proteus mirabilis (MIC = 32 ��g/mL), weakly inhibited Pseudomonas aeruginosa (MIC = 64 ��g/mL) and very weakly inhibited Staphylococcus aureus (MIC = 128 ��g/mL) and Enterococus faecalis (MIC = 128 ��g/mL).
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-11-29 |