6533b870fe1ef96bd12cfc60

RESEARCH PRODUCT

Highly selective electrosynthesis of biphenols on graphite electrodes in fluorinated media.

Gregor SchnakenburgItamar Michael MalkowskyFlorian SteckerSiegfried R. WaldvogelToshio FuchigamiAxel KirsteShotaro HayashiAndreas Fischer

subject

Organic ChemistryInorganic chemistryDiamondGeneral Chemistryengineering.materialElectrosynthesisElectrochemistryCombinatorial chemistryCatalysisCoupling reactionchemistry.chemical_compoundchemistryElectrodeengineeringPhenolOrganic synthesisGraphite

description

The direct and selective phenol coupling reaction that provides biphenols still represents a challenge in organic synthesis. The recently developed electrosynthesis on boron-doped diamond anodes with fluorinated additives was developed further to allow the application to less-expensive electrodes and fluorinated media. This advanced protocol allows the highly selective anodic phenol coupling reaction on graphite with a broad scope.

10.1002/chem.201102182https://pubmed.ncbi.nlm.nih.gov/22109730