6533b870fe1ef96bd12d03cb

RESEARCH PRODUCT

<b>ANTIMICROBIAL DITERPENOID ALKALOIDS FROM <i>ERYTHROPHLEUM SUAVEOLENS</i> (GUILL. & PERR.) BRENAN</b>

M-a.l. DuboisVeronique B PenlapB. L. SondengamFrançois-xavier EtoaR. N. ManfouoD. LontsiVictor KueteLéon Azefack TapondjouF. N. Ngounou

subject

Stem barkbiologyTraditional medicineChemistryStereochemistryErythrophleum suaveolensGeneral ChemistryAntimicrobialbiology.organism_classificationSpectral dataTerpenoid

description

An investigation of the stem bark of Erythrophleum suaveolens (Guill. & Perr.) Brenan yielded the known amide norcassaide ( 1 ) and a new diterpenoid alkaloid named norerythrosuaveolide ( 2 ) which was characterized as 7β-hydroxy-7-deoxo-6-oxonorcassaide. The structures were established on the basis of one and two-dimensional 1 H and 13 C NMR spectral data. The compounds showed potent antimicrobial activities against bacteria and yeasts. KEY WORDS: Erythrophleum suaveolens (Guill. & Perr.) Brenan, Norcassaide, Diterpenoid alkaloid, Norerythrosuaveolide, Antimicrobial activities, Bacteria, Yeasts Bull. Chem. Soc. Ethiop. 2005, 19(2), 221-226.

https://doi.org/10.4314/bcse.v19i2.21127