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RESEARCH PRODUCT
ChemInform Abstract: Baeyer-Villiger Oxidation of Ketones with a Silica-Supported Peracid in Supercritical Carbon Dioxide under Flow Conditions.
Gregorio AsensioJavier Parra-carbonellMaría Elena González-núñezAndrea OlmosRossella Mellosubject
chemistry.chemical_compoundSupercritical carbon dioxidechemistryYield (chemistry)ReagentCarbon dioxideOrganic chemistryDehydrogenationGeneral MedicineHydrogen peroxideBaeyer–Villiger oxidationBar (unit)description
[2-Percarboxyethyl]-functionalized silica reacts with ketones in supercritical carbon dioxide at 250 bar and 40 °C under flow conditions to yield the corresponding esters and lactones. The solid reagent can be easily recycled through treatment with 70% hydrogen peroxide in the presence of an acid at 0 °C. This procedure not only simplifies the isolation of the reaction products, but has the advantage of using only water and carbon dioxide as solvents under mild conditions.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2009-11-24 | ChemInform |