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RESEARCH PRODUCT
Has innate immunity evolved through different routes?
Nicolò Parrinellosubject
Intrinsic immunityGeneticsInnate immune systemEvolutionanimal diseasesmedia_common.quotation_subjectinvertebrateGeneral Physics and Astronomychemical and pharmacologic phenomenabiochemical phenomena metabolism and nutritionBiologyImmune systemDownregulation and upregulationArtificial IntelligenceImmunityImmunologybacteriaMetamorphosisMatingGeneral Agricultural and Biological SciencesGeneinnate immunitymedia_commondescription
Invertebrate self/non-self recognition, defense responses, mating and development share innate immune surveillance and functions challenged by competition and linked to fitness. Independent evolutionary branches of immune responses may use conserved gene traits. On the other hand immunity genes may be conserved due to their role in development. Finally, upregulation of innate immunity genes during ascidian metamorphosis supports the danger hypothesis.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2010-03-01 |