6533b872fe1ef96bd12d376c

RESEARCH PRODUCT

ChemInform Abstract: Thermal 1,6-Electrocyclization Reactions of Acceptor-Substituted 2,3-Divinyl-1H-indoles Yielding Functionalized Carbazoles.

Ulf PindurReinhard Adam

subject

ChemistryWittig reactionGeneral MedicineCombinatorial chemistryAcceptor

description

Three new synthetic procedures for and thermal 1,6-electrocyclizations of acceptor-substituted 2,3-divinyl-1H-indoles leading to functionalizing carbazoles are described. The scope and limitations as well as some mechanistic aspects of the methodologies are discussed. The key strategies employed include Pd(II)-catalyzed coupling and Wittig procedures.

https://doi.org/10.1002/chin.199040177