Interleukin-6 and Soluble Interleukin-6 Receptor: Direct Stimulation of gp130 and Hematopoiesis

6533b872fe1ef96bd12d4399

RESEARCH PRODUCT

Interleukin-6 and Soluble Interleukin-6 Receptor: Direct Stimulation of gp130 and Hematopoiesis

Albrecht M. Müller Malte Peters Stefan Rose John

subject

Models Molecular endocrine system medicine.medical_specialty Recombinant Fusion Proteins Immunology Mice Transgenic Leukemia inhibitory factor receptor Oncostatin M Biology Ciliary neurotrophic factor Biochemistry Designer Drugs Mice Structure-Activity Relationship Antigens CD Internal medicine Cytokine Receptor gp130 medicine Animals Humans Interleukin 6 Membrane Glycoproteins Interleukin-6 Oncostatin M Oncostatin M receptor Cell Differentiation Receptors Interleukin Cell Biology Hematology Hematopoietic Stem Cells Glycoprotein 130 Receptors Interleukin-6 Molecular biology Hematopoiesis Endocrinology Liver Solubility biology.protein Signal transduction Peptides Leukemia inhibitory factor Spleen

description

T HE INTERLEUKIN-6 (IL-6) family of cytokines acts via receptor complexes that contain at least one subunit of the signal transducing protein gp130.[1][1] The family comprises IL-6, IL-11, ciliary neurotrophic factor (CNTF), cardiotrophin-1 (CT-1), leukemia inhibitory factor (LIF), and oncostatin M

year	journal	country	edition	language
1998-11-15	Blood

https://doi.org/10.1182/blood.v92.10.3495

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