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RESEARCH PRODUCT
Determination of Caffeine in Analgesic Formulations Using the Apparent Content Curves Method
C. Pascual MartiM. Llobat EstellésA. R. Maurí AucejoA. Cerdán Vidalsubject
ChromatographyBiochemistry (medical)Clinical BiochemistryAnalgesicAnalytical chemistryBiochemistryHigh-performance liquid chromatographyDosage formAnalytical Chemistrychemistry.chemical_compoundUltraviolet visible spectroscopychemistryContent (measure theory)ElectrochemistryTernary operationCaffeineQuantitative analysis (chemistry)Spectroscopydescription
Abstract The determination of caffeine by UV spectroscopy in pharmaceutical samples, containing different compounds which provide spectral interferences as aspirin, paracetamol, chlorfeniramine or propylphenazone, is carried out. The proposed procedure is based on the apparent content curves method in order to resolve binary, ternary and multicomponent mixtures. Results obtained are, in all cases, in agreement with contents found by a HPLC procedure used as reference method.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1994-09-01 | Analytical Letters |