6533b873fe1ef96bd12d5933

RESEARCH PRODUCT

Additional file 2: of Trabectedin triggers direct and NK-mediated cytotoxicity in multiple myeloma

Maria CucèMaria Gallo CantafioMaria SicilianoCaterina RiilloDaniele CaraccioloFrancesca SciontiNicoletta StaropoliValeria ZuccalàLorenza MalteseAnna Di VitoKatia GrilloneVito BarbieriMariamena ArbitrioMaria Di MartinoMarco RossiNicola AmodioPierosandro TagliaferriPierfrancesco TassoneCirino Botta

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Figure S1. A Meta-analysis of 4 different GEP datasets of MM comparing the expression levels of genes belonging to different DNA-repair pathways (BER, MMR, HR, c-NHEJ, a-NHEJ, FA) in PCs from MM patients with PCs from healthy donors. B For each panel: on the left, forest plot showing the results of the multivariate COX regression analysis performed on all genes included in the specific DNA repair system. On the right, Kaplan-Meyer curve report results of prognostic system in which patients were divided into “low” and “high” risk group, according to the expression of genes identified by previous multivariate analysis. (PDF 605 kb)

https://dx.doi.org/10.6084/m9.figshare.7879124