Three-Dimensional Heterocycles by 5-exo-dig Cyclizations of S-Methyl-N-ynonylsulfoximines

6533b874fe1ef96bd12d5ff0

RESEARCH PRODUCT

Three-Dimensional Heterocycles by 5-exo-dig Cyclizations of S-Methyl-N-ynonylsulfoximines

Deshen Kong Kari Rissanen Ding Ma Khai-nghi Truong Carsten Bolm Chenyang Wang

subject

Range (particle radiation)Chemistry Dig Organic Chemistry Physical and Theoretical Chemistry Biochemistry Medicinal chemistry

description

Upon treatment with Cs2CO3, S-methyl-N-ynonylsulfoximines undergo 5-exo-dig cyclizations to give three-dimensional heterocycles. The reactions proceed at ambient temperature with a wide range of substrates affording the corresponding products in good to excellent yields.

year	journal	country	edition	language
2021-10-12	Organic Letters

https://doi.org/10.1021/acs.orglett.1c03041

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