6533b874fe1ef96bd12d6427

RESEARCH PRODUCT

The Fluoro-Pauson-Khand Reaction in the Synthesis of Enantioenriched Nitrogenated Bicycles Bearing a Quaternary C-F Stereogenic Center

Raquel RománDaniel M. SedgwickMercedes Medio-simónAlberto LlobatSantos FusteroNatalia MateuPablo Barrio

subject

010405 organic chemistryChemistryStereochemistryPauson–Khand reactionOrganic ChemistryPhysical and Theoretical Chemistry010402 general chemistry01 natural sciencesBiochemistry0104 chemical sciencesStereocenter

description

The authors are grateful to the Spanish MICINN and the AEI (CTQ2017-84249-P) for financial support, the SCSIE (Universitat de Valencia) for access to instrumental facilities, and M. ̀ R. Pedrosa (Universidad de Burgos) for providing us with MoO2Cl2. The technical and human support provided by SGIker (UPV/EHU, MINECO, GV/DJ, ERDF, and ESF) is also gratefully acknowledged. P.B. thanks the Spanish Ministry of Economy for a Ramon y Cajal contract (RyC-2016-20951). ́ The authors are also grateful to Jose Cabeza for assistance in the synthesis of certain starting materials.

10.1021/acs.orglett.9b02557http://hdl.handle.net/10651/53806