6533b874fe1ef96bd12d64de

RESEARCH PRODUCT

Systematic study of SYBR green chromophore reveals major improvement with one heteroatom difference

Ville K. SaarnioJohanna M. AlarantaTanja M. Lahtinen

subject

väriaineetsynteettiset väriaineetsense organsvalokemiamerkkiaineet

description

Five nucleic acid binding cyanine dyes were synthesized and their photophysical properties were evaluated. Changing a single heteroatom in the chromophore causes major differences both in brightness and photostability between the dyes. With such alteration, the brightness of the chromophore increased two-fold compared to the one found in SYBR Green I. peerReviewed

http://urn.fi/URN:NBN:fi:jyu-202105203054