6533b882fe1ef96bd12db709

RESEARCH PRODUCT

Additional file 4 of Co-administration of human MSC overexpressing HIF-1�� increases human CD34+ cell engraftment in vivo

Silvia PreciadoM�� Salom�� Sirerol-piquerSandra Munti��nLika OsuguiGerardo J. Mart��-chill��nAlmudena Navarro-bail��nPilar Sep��lvedaFerm��n S��nchez-guijo

subject

surgical procedures operative

description

Additional file 4. Figure S3. Analysis of human hematopoietic engraftment in spleen. Human hematopoietic engraftment was evaluated by flow cytometry after xenotrasplantation in NOD/SCID mice. The percentage of human CD45+ cells (donor chimerism) was analyzed in total spleen samples 4 weeks after transplantation. Mice were transplanted intravenously with CD34+ cells alone or co-transplanted with MSC WT or HIF-MSC, that were administered in the right femur. Data are represented as mean of 8 experiments for mice transplanted with CD34+ cells alone, 13 experiments for mice co-transplanted with CD34+ cells and WT MSC and 15 experiments for mice transplanted with CD34+ cells and HIF-MSC. p:n.s means p > 0.05

https://dx.doi.org/10.6084/m9.figshare.17141128