6533b883fe1ef96bd12dd32a
RESEARCH PRODUCT
Additional file 3: of KIAA0556 is a novel ciliary basal body component mutated in Joubert syndrome
Anna SandersErik De VriezeAnas AlazamiFatema AlzahraniErik MalarkeyNasrin SoruschLars TebbeStefanie KuhnsTeunis Van DamAmal AlhashemBrahim TabarkiQianhao LuNils LambacherJulie KennedyRachel BowieLisette HetterschijtSylvia Van BeersumJeroen Van ReeuwijkKarsten BoldtHannie KremerRobert KestersonDorota MoniesMohamed AbouelhodaRonald RoepmanMartijn HuynenMarius UeffingRob RussellUwe WolfrumBradley YoderErwin Van WijkFowzan AlkurayaOliver Blacquesubject
fungidescription
Ciliary phenotypes that are unaffected in C. elegans K04F10.2( tm1830 ) mutants. a K04F10.2 mutants possess normal fluorescent dye (DiI) filling in amphid (head) and phasmid (tail) neurons. Scale bars, 15 μm. b The lengths and morphologies of various sensory neuronal cilia are normal in K04F10.2 mutants. Shown are fluorescence images of cilia from worms expressing str-1p::GFP (AWB neuron), gcy-5p::GFP (ASER neuron) and OSM-6::GFP (PHA/B neurons) transgenes. Numbers (± standard error of the mean) refer to cilium lengths. Scale bars, 2 μm. c–e K04F10.2 mutants possess normal sensory benzaldehyde chemoattraction (n = 10), osmotic avoidance (n = 10), and foraging/roaming (n = 34) behaviours. che-11(e1810) and osm-5(p813) are negative controls. *p
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-01-01 |