6533b883fe1ef96bd12dda47

RESEARCH PRODUCT

Additional file 7: of KIAA0556 is a novel ciliary basal body component mutated in Joubert syndrome

Anna SandersErik De VriezeAnas AlazamiFatema AlzahraniErik MalarkeyNasrin SoruschLars TebbeStefanie KuhnsTeunis Van DamAmal AlhashemBrahim TabarkiQianhao LuNils LambacherJulie KennedyRachel BowieLisette HetterschijtSylvia Van BeersumJeroen Van ReeuwijkKarsten BoldtHannie KremerRobert KestersonDorota MoniesMohamed AbouelhodaRonald RoepmanMartijn HuynenMarius UeffingRob RussellUwe WolfrumBradley YoderErwin Van WijkFowzan AlkurayaOliver Blacque

subject

description

Supplementary information to the data in Fig. 8 . a Schematic representation of all the different KIAA0556 fragments used to screen our selection of 200+ ciliary proteins. The predicted protein repeat domains, shown in Additional files 1 and 2, are depicted as d1 to d4. Constructs were generated containing isolated domains as well as a combination of domains. b Single transfections of PalMyr-KIAA0556 and mRFP-KATNBL1, showing that membrane localisation of the mRFP tagged protein is indeed dependent on the interaction with the PalMyr-tagged protein. (JPG 491 kb)

https://dx.doi.org/10.6084/m9.figshare.c.3613589_d2.v1