Enterococcus ģints baktēriju identifikācija un vankomicīna rezistences gēnu noteikšana

6533b884fe1ef96bd12de995

RESEARCH PRODUCT

Enterococcus ģints baktēriju identifikācija un vankomicīna rezistences gēnu noteikšana

subject

vanB E. faecium VRE E. faecalis vanA Medicīna

description

Pēdējo gadu laikā pasaulē strauji pieaug enterokoku rezistence pret dažādu grupu antimikrobajiem līdzekļiem un to izraisītas infekciju slimības, īpaši, nozokomiālas. Pētījuma mērķis bija noteikt no klīniskā materiāla izolēto enterokoku antibakteriālo jutību, kā arī noteikt vankomicīna rezistences gēnus. Enterococcus sp. celmu antimikrobiālā jutība tika noteikta izmantojot Kirby-Bauer disku difūzijas metodi, savukārt vankomicīna rezistences gēni enterokokos tika identificēti izmantojot Genotype Enterococcus testu. Rezumējot pētījuma datus visvairāk tika identificētas divas enterokoku sugas – E.faecalis (81 %) un E.faecium (19 %). E. faecium bija rezistentāks pret pētījumā izmantotajiem antimikrobajiem līdzekļiem kā E. faecalis. Izmantojot Genotype Enterococcus testu tika identificēti septiņi E.faecium celmi no desmit ņemtajiem paraugiem. Sešiem E.faecium celmiem tika noteikti vanB rezistences gēni.

year	journal	country	edition	language
2018-01-01

https://dspace.lu.lv/dspace/handle/7/40221

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