Search results for " 11"
showing 10 items of 591 documents
18-hydroxylation in the Y-1 adrenal cell line: response to ACTH and to culture conditions.
1992
The 18-hydroxylation of deoxycorticosterone in the Y-1 adrenal cell line was studied under various incubation and cell culture conditions and compared to 11 beta-hydroxylation. Repeated incubation of the substrate increased both 18- and 11 beta-hydroxylation in the Y-1 cells. Furthermore, both 18- and 11 beta-hydroxylation were increased with increased serum concentration and prolonged incubation time. While the increase in 11 beta-hydroxylation seemed to be independent of the type of serum, 18-hydroxylation was much more important in cells cultured in fetal or newborn calf serum supplemented medium than in those cultured in horse serum supplemented medium. As expected, ACTH treatment incre…
Translocation (10;11;22)(p14;q24;q12) Characterized by Fluorescence in Situ Hybridization in a Case of Ewing's Tumor
2001
It is well recognized that the identification by classic cytogenetics of t(11;22)(q24;q12) is a useful aid in the accurate diagnosis of Ewing's sarcoma and related tumors. This translocation induces the EWS/FLI-1 fusion transcript, which can be detected by reverse transcription-polymerase chain reaction. Recent studies have also used fluorescence in situ hybridization (FISH) to demonstrate the translocation. The authors coupled classic cytogenetics and FISH on tumor cells from the original specimen, the local recurrence, and the pulmonary metastasis as well as from the xenografted tumors in a case of extraosseous Ewing's sarcoma. FISH analysis not only confirmed the cytogenetic results but …
Recent Insights Into Cyberchondria.
2020
Purpose of Review The construct of cyberchondria was introduced relatively recently. This article aims to review the conceptualization, theoretical basis and correlates of cyberchondria, as well as its prevention and management. Recent Findings Although there is no consensus, most definitions of cyberchondria emphasize online health research associated with heightened distress or anxiety. The two theoretical models of cyberchondria involve reassurance seeking and specific metacognitive beliefs. Cyberchondria has relationships with health anxiety, problematic Internet use and symptoms of obsessive-compulsive disorder, with public health implications pertaining to functional impairment and al…
[Adverse reactions to human papillomavirus vaccine in the Valencian Community (2007-2011)].
2014
Introduction: In 2009, two cases of seizures in adolescents following quadrivalent human papillomavirus vaccine (qHPV) administration generated important media attention, and adversely affected public trust in this vaccine. Our objectives were to describe suspected adverse reactions (SARs) reported to the Pharmacovigilance Centre in the Valencian Community (PCVC) after administration of HPV vaccine, and to compare reporting rates of syncope and seizures following this vaccine with those of other vaccines administered to girls aged 13–15 years. Materials and methods: Descriptive study of SARs reported following administration of this vaccine to the PCVC between 2007 and 2011. Results: The cl…
Should kidney allografts from old donors be allocated only to old recipients?
2020
Contains fulltext : 226016.pdf (Publisher’s version ) (Closed access) In several deceased donor kidney allocation systems, organs from elderly donors are allocated primarily to elderly recipients. The Eurotransplant Senior Program (ESP) was implemented in 1999, and since then, especially in Europe, the use of organs from elderly donors has steadily increased. The proportion of ≥60-year-old donors reported to the Collaborative Transplant Study (CTS) by European centers has doubled, from 21% in 2000-2001 to 42% in 2016-2017. Therefore, in the era of organ shortage it is a matter of debate whether kidney organs from elderly donors should only be allocated to elderly recipients or whether <65-y…
INHIBITION OF CELLULAR GROWTH AND STEROID 11β-HYDROXYLATION INRAS-TRANSFORMED ADRENOCORTICAL CELLS BY THE FUNGAL TOXINS BETICOLINS
1996
Abstract The proliferation of GM16 and 4CDTras-transformed newborn rat adrenocortical (RTAC) cells and Y1 mouse adrenal tumor cells was inhibited by beticolins, the fungal toxins extracted fromCercospora beticola, at submicromolar concentrations in a dose-dependent manner. Inhibitory concentrations for half the maximum inhibition were 150, 75 and 25 n M for beticolin-1 and 230, 150 and 50 n M for beticolin-2 in GM16, 4CDT and Y1 cells respectively. Beticolins strongly inhibited the production of 11β-hydroxysteroids on the second and third days of treatment in a dose-dependent manner between 0.1 and 1 μ M . Beticolins were shown by confocal microscopy to be localized in cytoplasmic organelle…
Terrorismin vastaisen sodan poliittisuus : Tony Blairin puheet syyskuun yhdennestätoista Afganistanin sotaan romanttisena narratiivina
2008
Tämän tutkimuksen tarkoituksena on selvittää terrorismin vastaisen sodan poliittinen merkitys, jota etsitään Tony Blairin pitämistä puheista syyskuun yhdennentoista terroristiiskujen ja Afganistanin sodan välisenä aikana. Poliittisena perspektiivinä on hyödynnetty saksalaisen poliittisen teoreetikon Carl Schmittin (1888–1985) määritelmää poliittisesta ystävä/ vihollinen –erotteluna, johon sisältyy sodan mahdollisuus. Tämän lisäksi tutkimuksessa on sovellettu Schmittin käsitystä konkreettisesta järjestyksestä, joka koostuu relatiivisen homogeenisyyden jakavista poliittisista entiteeteistä, ja partisaanista, joka tarjoaa implisiittisen määritelmän terroristista. Tutkimuksen aineisto koostuu T…
Ecclesiasticità minima delle confraternite e organizzazioni di volontariato (la Legge 266/1991 contiene un invito implicito alla deconfessionalizzazi…
2010
Il contributo, traendo spunto dalla disamiina di una pronuncia del T.A.R. Veneto (15 gennaio 2009, n.620) affronta il tema dell'applicabilità della normativa sul volontariato alle associazioni laicali d'indole confessionale.
Soil quality - Method to directly extract DNA from Soil Samples. ISO/ DIS 11063
2010
DNA (deoxy ribonucleic acids) is an essential component of any living organisms coding for enzymes responsible for any biological activities. The study of DNA sequences from DNA sources extracted from different matrixes, by means of numerous molecular approaches, provides molecular markers that can be used to sharply distinguish and identify different organisms (bacteria, archaea and eucaryotes). Up to now, most of the studies aiming to develop microbial soil quality indicators applicable to complex environment, such as soil, were biased by the unculturability of many microorganisms and the lack of sensitivity of traditional microbiological methods. The recent development of numerous molecu…
Assessment of genetically modified oilseed rape MS8, RF3 and MS8×RF3 for renewal of authorisation under regulation (EC) No 1829/2003 (application EFS…
2017
Efsa Panel On Genetically Modified Organisms (gmo)Opinion scientificRequestor: European CommissionQuestion number: EFSA-Q-2016-00569; Following the submission of application EFSA-GMO-RX-004 under Regulation (EC) No 1829/2003 from Bayer CropScience, the Panel on Genetically Modified Organisms of the European Food Safety Authority (GMO Panel) was asked to deliver a scientific risk assessment on the data submitted in the context of the renewal of authorisation application of the genetically modified (GM) herbicide-tolerant oilseed rape MS8, RF3 and MS89RF3. The data received in the context of this renewal application contain post-market environmental monitoring reports, systematic searches and…