Search results for " 50"

showing 10 items of 2715 documents

Assessment of the cytotoxic potential of an aqueous-ethanolic extract from Thalassia testudinum angiosperm marine grown in the Caribbean Sea

2018

Abstract Objectives Reported antioxidant, anti-inflammatory and neuroprotective properties for one aqueous-ethanolic extract from Thalassia testudinum which grows in the Caribbean Sea compelled us to explore about extract cytotoxic effects. Methods Cell viability was assayed on tumour (HepG2, PC12, Caco-2 and 4T1) and non-tumour (VERO, 3T3, CHO, MCDK and BHK2) cell lines. The extract effects upon primary cultures of rat and human hepatocytes and human lymphocytes were assayed. Key findings The extract exhibited cytotoxicity against cancer cells compared to normal cells, and the IC50 values were 102 μg/ml for HepG2, 135 μg/ml for PC12, 165 μg/ml for Caco-2 and 129 μg/ml for 4T1 cells after 4…

AdultMale0301 basic medicineCell SurvivalDNA damagePrimary Cell CulturePharmaceutical ScienceHydrocharitaceaePC12 CellsRats Sprague-DawleyInhibitory Concentration 5003 medical and health sciencesNeoplasmsAnimalsHumansCytotoxic T cellLymphocytesViability assayCytotoxicityPharmacologyDose-Response Relationship DrugEthanolbiologyPlant ExtractsChemistryPharmacology. TherapyWaterHep G2 Cellsbiology.organism_classificationAntineoplastic Agents PhytogenicMolecular biologyRatsComet assay030104 developmental biologyCaribbean RegionCell cultureThalassia testudinumCancer cellSolventsCaco-2 CellsThalassia testudinum DNA damage cytotoxicity oxidative stressJournal of pharmacy and pharmacology
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Towards Improved Healthcare Performance: Examining Technological Possibilities and Patient Satisfaction with Wireless Body Area Networks

2009

Published version of an article from the journal: Journal of Medical Systems. he original publication is available at Springerlink. http://dx.doi.org/10.1007/s10916-009-9291-8 This paper investigates the benefits of using less intrusive wireless technologies for heart monitoring. By replacing well established heart monitoring devices (i.e. Holter) with wireless ECG based Body Area Networks (BAN), improved healthcare performance can be achieved, reflected in (1) high quality ECG recordings during physical activities and (2) increased patient satisfaction. A small scale clinical trial was conducted to compare both technologies and the results illustrate that the wireless ECG monitor was able …

AdultMaleTelemedicineAdolescentComputer scienceRemote patient monitoringmedicine.medical_treatmentmedia_common.quotation_subjecteducationMedicine (miscellaneous)Health InformaticsHealth informaticsYoung AdultPatient satisfactionHealth Information ManagementmedicineHumansWirelessVDP::Medical disciplines: 700::Health sciences: 800::Health service and health administration research: 806ComputerSystemsOrganization_SPECIAL-PURPOSEANDAPPLICATION-BASEDSYSTEMSQuality (business)cardiovascular diseasesChildAgedmedia_commonbusiness.industryLocal area networkArrhythmias CardiacVDP::Technology: 500::Information and communication technology: 550Middle AgedLocal Area Networksequipment and suppliesTelemedicineRisk analysis (engineering)Patient SatisfactionElectrocardiography AmbulatoryFemaleCardiac monitoringbusinessTelecommunicationsInformation Systems
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Clinical evaluation of a wireless ECG sensor system for arrhythmia diagnostic purposes

2013

Accepted version of an article in the journal: Medical Engineering and Physics. Also available from the publisher at: http://dx.doi.org/10.1016/j.medengphy.2013.03.002 In a clinical study, a novel wireless electrocardiogram (ECG) recorder has been evaluated with regard to its ability to perform arrhythmia diagnostics. As the ECG recorder will detect a "non-standard" ECG signal, it has been necessary to compare those signals to "standard" ECG recording signals in order to evaluate the arrhythmia detection ability of the new system. Simultaneous recording of ECG signals from both the new wireless ECG recorder and a conventional Holter recorder was compared by two independent cardiology specia…

AdultMalemedicine.medical_specialtyambulatory electrocardiographyBiomedical EngineeringBiophysicsElectrocardiographyYoung Adultevaluation studiesmedicineHumansWirelessMedical physicscardiovascular diseasesChildReference standardsAgedAmbulatory electrocardiographySensor systemclinical trialsbusiness.industryReproducibility of ResultsArrhythmias CardiacSignal Processing Computer-AssistedVDP::Technology: 500::Information and communication technology: 550Middle AgedReference StandardsHolter monitoringClinical trialVDP::Medical disciplines: 700wireless ECG sensorFemalebusinessTelecommunicationsWireless TechnologyClinical evaluationHolter monitoring
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Research on Acute Toxicity and the Behavioral Effects of Methanolic Extract from Psilocybin Mushrooms and Psilocin in Mice

2015

The pharmacological activities and acute toxicity of the psilocin (PC) and dried residues of the crude extracts of psychotropic mushrooms were investigated in mice. The hallucinogenic substances were effectively isolated, by using methanol, from the species of Psilocybe semilanceata and Pholiotina cyanopus, that were collected in the north-east region of Poland. The chemical analysis of these extracts, which was performed by liquid chromatography with mass spectrometry detection (LC-MS), indicated the presence of psilocin and other hallucinogenic substances, including indolealkylamines and their phosphorylated analogues. When the pure psilocin or fungal extracts were used, slight difference…

Agonistmedicine.drug_classHealth Toxicology and Mutagenesislcsh:Medicineacute toxicityComplex MixturesPharmacologyToxicologyhead-twitch response (HTR)Median lethal dosePartial agonistArticlePsilocybinLethal Dose 50MiceAnimals Outbred StrainsmedicineAnimalspsilocybin mushrooms; psilocin; acute toxicity; head-twitch response (HTR)psilocinBehavior AnimalbiologyChemistryMethanollcsh:Rpsilocybin mushroomsbiology.organism_classificationAcute toxicityPsilocybin<i>head-twitch</i> response (HTR)PsilocinToxicityHallucinogensSolventsPsilocybe semilanceataFemaleAgaricalesmedicine.drugToxins
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Survey data regarding perceived air quality in Australia, Brazil, China, Ghana, India, Iran, Italy, Norway, South Africa, United States before and du…

2020

The dataset deals with the air quality perceived by citizens before and during the enforcement of COVID-19 restrictions in ten countries around the world: Australia, Brazil, China, Ghana, India, Iran, Italy, Norway, South Africa and the United States. An online survey conveniently translated into Chinese, English, Italian, Norwegian, Persian, Portuguese collected information regarding the perceived quality of air pollution according to a Likert scale. The questionnaire was distributed between 11-05-2020 and 31-05-2020 and 9 394 respondents took part. Both the survey and the dataset (stored in a Microsoft Excel Worksheet) are available in a public repository. The collected data offer the peo…

Air pollutionEnvironmental pollutionlcsh:Computer applications to medicine. Medical informaticsmedicine.disease_causeArticleEnvironmental pollutionLikert scale03 medical and health sciences0302 clinical medicineSurvey datamedicinelcsh:Science (General)SocioeconomicsChinaAir quality index030304 developmental biologyPersian0303 health sciencesMultidisciplinaryVDP::Technology: 500COVID-19Psychometric perceptionlanguage.human_languageGeographyAir qualitylanguagelcsh:R858-859.7Survey data collectionPortuguese030217 neurology & neurosurgerylcsh:Q1-390Data in Brief
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Alkaline fuel cell technology - A review

2021

Abstract The realm of alkaline-based fuel cells has with the arrival of anionic exchange membrane fuel cells (AEMFCs) taken a great step to replace traditional liquid electrolyte alkaline fuel cells (AFCs). The following review summarises progress, bottleneck issues and highlights the most recent research trends within the field. The activity of alkaline catalyst materials has greatly advanced, however achieving long-term stability remains a challenge. Great AEMFC performances are reported, though these are generally obtained through the employment of platinum group metals (PGMs), thus emphasising the importance of R&D related to non-PGM materials. Thorough design strategies must be utilise…

Alkaline fuel cellMaterials scienceRenewable Energy Sustainability and the Environmentbusiness.industryEnergy Engineering and Power Technology02 engineering and technology010402 general chemistry021001 nanoscience & nanotechnologyCondensed Matter Physics01 natural sciences0104 chemical sciencesVDP::Teknologi: 500Fuel TechnologyFuel cells0210 nano-technologyProcess engineeringbusinessAlkaline catalystInternational Journal of Hydrogen Energy
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LTE-based passive radars and applications: a review

2021

This paper provides an overview of the most recent passive radars based on long-term evolution (LTE). To begin, this paper investigates the various characteristics and requirements of 4 G LTE signals for radar, taking performance aspects such as range, velocity, range resolution, and velocity resolution into account. An ambiguity function analysis is performed on a measured LTE signal using the synchronization and reference signal components to evaluate key performance parameters such as Doppler and range characteristics. We also discuss how LTE passive radar can be used in a variety of applications. The detailed analysis of the LTE downlink signal, its structural overview, and the effect o…

Ambiguity functionbusiness.industryComputer scienceSignalSynchronizationPassive radarlaw.inventionsymbols.namesakelawTelecommunications linksymbolsElectronic engineeringGeneral Earth and Planetary SciencesWirelessRadarbusinessDoppler effectVDP::Teknologi: 500::Informasjons- og kommunikasjonsteknologi: 550
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Synthesis and biological activities of a new class of heat shock protein 90 inhibitors, designed by energy-based pharmacophore virtual screening

2013

The design through energy-based pharmacophore virtual screening has led to aminocyanopyridine derivatives as efficacious new inhibitors of Hsp90. The synthesized compounds showed a good affinity for the Hsp90 ATP binding site in the competitive binding assay. Moreover, they showed an excellent antiproliferative activity against a large number of human tumor cell lines. Further biological studies on the derivative with the higher EC50 confirmed its specific influence on the cellular pathways involving Hsp90.

AminopyridinesInhibitory Concentration 50Structure-Activity RelationshipUser-Computer InterfaceHeat shock proteinCell Line TumorSettore BIO/10 - BiochimicaDrug DiscoveryHumansHSP90 Heat-Shock ProteinsBinding siteVirtual screeningheat shock protein 90 inhibitors energy-based pharmacophore virtual screening cell cycle antiproliferative activitybiologyChemistryHsp90Combinatorial chemistrySettore CHIM/08 - Chimica FarmaceuticaHuman tumorMolecular Docking SimulationCell cultureDrug DesignEnergy basedbiology.proteinMolecular MedicinePharmacophoreDrug Screening Assays Antitumor
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Effect of substrate improvement on optimising biogas yield from anaerobic digestion

2014

Masteroppgave i fornybar energi ENE 500 Universitetet i Agder 2014 The anaerobic digestion process involves the decomposition of the organic matter to yield biogas; gas that is mainly composed of methane and carbon dioxide with traces of some other gases. This process is used for different purposes including municipal waste treatment, wastewater treatment, fertilizer production, and farm wastes disposal as well as energy production. It is accomplished in three main stages; hydrolysis, acidogenesis and methanogenesis with each of the stages achieved by specific microorganisms that are active in limited ranges of operational and environmental conditions. These conditions are controlled to ach…

Anaerobic Digestion ; Biogas Yield ; Substrates ; Food wastes ; Fruit wastes ; Characterisation ; renewable energyENE500VDP::Technology: 500
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The Gender Gap in Online Shopping in Turkey

2022

The main aim of this study is to explore the gender gap in online shopping in the Turkish population. The gender gap in internet use and online shopping is investigated using the results of annual national surveys on Information and Communication Technology (ICT) Usage in Households and by Individuals by the Turkish Statistical Institute (TurkStat). The study results reveal that females in Turkey tend to be on the wrong side of the digital divide. Even though internet use has increased over the years in the Turkish population, there remains a significant and persistent gap between females and males in internet use and online shopping. It is also found that there are differences between fema…

Anesthesiology and Pain MedicineVDP::Teknologi: 500::Informasjons- og kommunikasjonsteknologi: 550
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