Search results for " AD"

showing 10 items of 18632 documents

Hierarchy is Detrimental for Human Cooperation

2015

Studies of animal behavior consistently demonstrate that the social environment impacts cooperation, yet the effect of social dynamics has been largely excluded from studies of human cooperation. Here, we introduce a novel approach inspired by nonhuman primate research to address how social hierarchies impact human cooperation. Participants competed to earn hierarchy positions and then could cooperate with another individual in the hierarchy by investing in a common effort. Cooperation was achieved if the combined investments exceeded a threshold, and the higher ranked individual distributed the spoils unless control was contested by the partner. Compared to a condition lacking hierarchy, c…

0106 biological sciences0301 basic medicineAdultMalegenetic structuresAdolescentMatemáticasControl (management)Hierarchy Social010603 evolutionary biology01 natural sciencesArticleMicroeconomics03 medical and health sciencesYoung AdultGame TheoryHumansCooperative BehaviorSocial influenceHierarchyMultidisciplinarySocial environmentMiddle AgedSocial stratificationSocial dynamics030104 developmental biologyGeneral partnershipFemaleBusinessGame theoryScientific Reports
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Daily rhythmicity of high affinity copper transport

2016

A differential demand for copper (Cu) of essential cupro-proteins that act within the mitochondrial and chloroplastal electronic transport chains occurs along the daily light/dark cycles. This requires a fine-tuned spatiotemporal regulation of Cu delivery, becoming especially relevant under non-optimal growth conditions. When scarce, Cu is imported through plasma membrane-bound high affinity Cu transporters (COPTs) whose coding genes are transcriptionally induced by the SPL7 transcription factor. Temporal homeostatic mechanisms are evidenced by the presence of multiple light- and clock-responsive regulatory cis elements in the promoters of both SPL7 and its COPT targets. A model is presente…

0106 biological sciences0301 basic medicineCircadian clockArabidopsisComputingMilieux_LEGALASPECTSOFCOMPUTINGPlant Science01 natural sciencesElectron Transport03 medical and health sciencesGene Expression Regulation PlantArabidopsisBotanyRNA MessengerSLC31 ProteinsPromoter Regions GeneticCation Transport ProteinsTranscription factorbiologyArabidopsis ProteinsGiganteaTransporterPromoterbiology.organism_classificationElectron transport chainArticle AddendumCircadian RhythmTransport proteinDNA-Binding Proteins030104 developmental biologyBiophysicsCopperMetabolic Networks and PathwaysTranscription Factors010606 plant biology & botanyPlant Signaling & Behavior
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Northern European Salmo trutta (L.) populations are genetically divergent across geographical regions and environmental gradients

2020

The salmonid fish Brown trout is iconic as a model for the application of conservation genetics to understand and manage local interspecific variation. However, there is still scant information about relationships between local and large-scale population structure, and to what extent geographical and environmental variables are associated with barriers to gene flow. We used information from 3,782 mapped SNPs developed for the present study and conducted outlier tests and gene–environment association (GEA) analyses in order to examine drivers of population structure. Analyses comprised >2,600 fish from 72 riverine populations spanning a central part of the species' distribution in norther…

0106 biological sciences0301 basic medicineConservation geneticsSELECTIONPopulationsalmonidCONSERVATIONlcsh:Evolutiongenotype‐environment association010603 evolutionary biology01 natural sciencesGene flow03 medical and health sciencesbrown troutLOCAL ADAPTATIONSampling designlcsh:QH359-425GeneticsGENOME SCANS14. Life underwaterSalmoeducationEcology Evolution Behavior and SystematicsLocal adaptationGenotype‐environment associationeducation.field_of_studyCLIMATE-CHANGEbiologyBROWN TROUTSTRUCTURED POPULATIONSR-PACKAGESampling (statistics)genotype-environment associationVDP::Matematikk og Naturvitenskap: 400biology.organism_classification030104 developmental biologyEvolutionary biologyoutlier testTEMPORAL-CHANGESOutlierGeneral Agricultural and Biological SciencesASCERTAINMENT BIASlocal adaptation
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Deimatism: a neglected component of antipredator defence

2017

Deimatic or ‘startle’ displays cause a receiver to recoil reflexively in response to a sudden change in sensory input. Deimatism is sometimes implicitly treated as a form of aposematism (unprofitability associated with a signal). However, the fundamental difference is, in order to provide protection, deimatism does not require a predator to have any learned or innate aversion. Instead, deimatism can confer a survival advantage by exploiting existing neural mechanisms in a way that releases a reflexive response in the predator. We discuss the differences among deimatism, aposematism, and forms of mimicry, and their ecological and evolutionary implications. We highlight outstanding questions …

0106 biological sciences0301 basic medicineEscape responseAposematismBiology010603 evolutionary biology01 natural sciences03 medical and health sciencespredator–preyEscape ReactionFundamental differenceComponent (UML)ReflexcamouflageAnimalsSurvival advantageaposematismstartle reflexCognitive scienceBehaviorEvolutionary BiologyBehavior AnimalAnimalEcologyBiological SciencesAcripezabiology.organism_classificationBiological EvolutionAgricultural and Biological Sciences (miscellaneous)Sensory input030104 developmental biologywarning coloursAcripezaMimicryta1181Animal Behaviourpredator-preyGeneral Agricultural and Biological SciencesBiotechnology
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Very high MHC Class IIB diversity without spatial differentiation in the mediterranean population of greater Flamingos.

2017

WOS: 000397335400001

0106 biological sciences0301 basic medicineGene FlowGenotypeLocal adaptationPopulationGenes MHC Class II010603 evolutionary biology01 natural sciencesIntraspecific competitionGene flowMHC GenesBirds03 medical and health sciences[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisAnimals[ SDV.IMM ] Life Sciences [q-bio]/Immunology14. Life underwaterSelection GeneticeducationEcology Evolution Behavior and SystematicsAllelic diversity ; Local adaptation ; MHC genes ; Pathogen-mediated balancing selection ; Greater flamingosAllelesLocal adaptationeducation.field_of_studyGenetic diversitybiologyHistocompatibility Antigens Class IIGenetic VariationAllelic diversityMHC genesExonsbiology.organism_classificationPathogen-mediated balancing selection030104 developmental biologyEvolutionary biologyGreater flamingosBiological dispersal[SDV.IMM]Life Sciences [q-bio]/ImmunologyGreater flamingoAdaptation[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/SymbiosisResearch Article
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Demographic history has shaped the strongly differentiated corkwing wrasse populations in Northern Europe

2019

Understanding the biological processes involved in genetic differentiation and divergence between populations within species is a pivotal aim in evolutionary biology. One particular phenomenon that requires clarification is the maintenance of genetic barriers despite the high potential for gene flow in the marine environment. Such patterns have been attributed to limited dispersal or local adaptation, and to a lesser extent to the demographic history of the species. The corkwing wrasse (Symphodus melops) is an example of a marine fish species where regions of particular strong divergence are observed. One such genetic break occurred at a surprisingly small spatial scale (FST ~0.1), over a s…

0106 biological sciences0301 basic medicineGene FlowMaleReproductive IsolationDemographic historyphylogeography010603 evolutionary biology01 natural sciencesGene flow03 medical and health sciencesGenetic driftGeneticsAnimals14. Life underwaterEcology Evolution Behavior and Systematicspopulation genetics—empiricalLocal adaptationDemographyfishGenomebiologyEcologyGenetic DriftFisheslandscape geneticsVDP::Matematikk og Naturvitenskap: 400Reproductive isolationVDP::Mathematics and natural science: 400::Zoology and botany: 480::Zoogeography: 486VDP::Matematikk og Naturvitenskap: 400::Zoologiske og botaniske fag: 480::Zoogeografi: 486biology.organism_classificationEuropePhylogeography030104 developmental biologyaquacultureEvolutionary biologyBiological dispersalFemaleCorkwing wrasse
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Local adaptation of plant viruses: lessons from experimental evolution.

2016

[EN] For multihost pathogens, adaptation to multiple hosts has important implications for both applied and basic research. At the applied level, it is one of the main factors determining the probability and severity of emerging disease outbreaks. At the basic level, it is thought to be a key mechanism for the maintenance of genetic diversity both in host and pathogen species. In recent years, a number of evolution experiments have assessed the fate of plant virus populations replicating within and adapting to one single or to multiple hosts species. A first group of these experiments tackled the existence of trade-offs in fitness and virulence for viruses evolving either within a single hos…

0106 biological sciences0301 basic medicineGeneralistsGenotypeLocal adaptationAcclimatizationGenetic FitnessBiology010603 evolutionary biology01 natural sciencesHost SpecificityPlant VirusesEvolution Molecular03 medical and health sciencesPathosystemGeneticsGenetic PleiotropyEcology Evolution Behavior and SystematicsLocal adaptationGenetic diversityExperimental evolutionVirulenceGenetic VariationGenetic PleiotropyVirus evolutionSpecialists030104 developmental biologyExperimental evolutionEvolutionary biologyViral evolutionHost rangeAntagonistic pleiotropyGenetic FitnessAdaptationMolecular ecology
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Lipid Nanoparticles as Potential Gene Therapeutic Delivery Systems for Oral Administration.

2017

Background Gene therapy has experimented an increasing attention in the last decades, due to its enormous potential applications in the medical field. It can be defined as the use of genes or genetic material (DNA, RNA, oligonucleotides) to treat or prevent a disease state, generally a geneticbased one. Application Other applications, like treating viral, bacterial or parasite infections or development of vaccines are gaining also interest. Efficient gene therapy is mainly dependent on the ability of the highly labile genetic material to reach the therapeutic target. For this purpose, different delivery systems have been designed and extensively investigated. Nanoparticles offer a broad ran…

0106 biological sciences0301 basic medicineGenetic enhancementAdministration OralComputational biologyBiologyGene deliveryPharmacology01 natural sciences03 medical and health sciencesDrug Delivery SystemsOral administration010608 biotechnologyNucleic AcidsDrug DiscoverySolid lipid nanoparticleGeneticsOral routeAnimalsHumansParasite InfectionsMolecular BiologyGeneGenetics (clinical)Drug CarriersGene Transfer TechniquesGenetic TherapyBiocompatible materialLipids030104 developmental biologyMolecular MedicineNanoparticlesCurrent gene therapy
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Chironomus riparius(Diptera) genome sequencing reveals the impact of minisatellite transposable elements on population divergence

2016

AbstractActive transposable elements (TEs) may result in divergent genomic insertion and abundance patterns among conspecific populations. Upon secondary contact, such divergent genetic backgrounds can theoretically give rise to classical Dobzhansky-Muller incompatibilities (DMI), a way how TEs can contribute to the evolution of endogenous genetic barriers and eventually population divergence. We investigated whether differential TE activity created endogenous selection pressures among conspecific populations of the non-biting midgeChironomus riparius,focussing on aChironomus-specific TE, the minisatellite-likeCla-element, whose activity is associated with speciation in the genus. Using an …

0106 biological sciences0301 basic medicineGenome Insectved/biology.organism_classification_rank.speciesPopulationGenomicsMinisatellite RepeatsBiologyPolymorphism Single Nucleotide010603 evolutionary biology01 natural sciencesGenomeChironomidaeDNA sequencingEvolution Molecular03 medical and health sciencesNegative selectionGeneticsAnimalseducationIn Situ Hybridization FluorescenceEcology Evolution Behavior and SystematicsLocal adaptationGeneticsChironomus ripariuseducation.field_of_studyPolytene chromosomeved/biologyfood and beveragesGenetics Population030104 developmental biologyMinisatelliteEvolutionary biologyDNA Transposable ElementsFemaleMolecular Ecology
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A hierarchical Bayesian Beta regression approach to study the effects of geographical genetic structure and spatial autocorrelation on species distri…

2019

Global climate change (GCC) may be causing distribution range shifts in many organisms worldwide. Multiple efforts are currently focused on the development of models to better predict distribution range shifts due to GCC. We addressed this issue by including intraspecific genetic structure and spatial autocorrelation (SAC) of data in distribution range models. Both factors reflect the joint effect of ecoevolutionary processes on the geographical heterogeneity of populations. We used a collection of 301 georeferenced accessions of the annual plant Arabidopsis thaliana in its Iberian Peninsula range, where the species shows strong geographical genetic structure. We developed spatial and nonsp…

0106 biological sciences0301 basic medicineHierarchical Bayesian modelsArabidopsis thalianaRange (biology)Bayesian probabilitySpecies distributionArabidopsisGenetic admixtureBiologyResidual010603 evolutionary biology01 natural sciences03 medical and health sciencesAfrica NorthernStatisticsGeneticsSpatial analysisEcology Evolution Behavior and SystematicsSpatial AnalysisPortugalPlant DispersalGenetic heterogeneityGlobal climate changePhylogeographyGenetics Population030104 developmental biologySpainGenetic structureGeographic genetic structureMaxentPeptidesSpatial autocorrelationBiotechnology
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