Search results for " ADR"

Polyunsaturated fatty acids in cultured cardiomyocytes : effect on physiology and beta-adrenoceptor function

1992

This study was carried out to investigate the influence of the membrane fatty acid composition on the basal electrical and contractile activities and the response to beta-adrenergic stimulation of rat cardiac muscle cells in culture. Cells were grown for 3 days in a conventional serum culture medium and then incubated for 24 h in synthetic media containing either n-6 or n-3 as the sole source of polyunsaturated fatty acids (PUFA). The n-6/n-3 ratio in the phospholipids was 0.9 in the n-3 cells and 13.1 in the n-6 cells compared with 6.3 in controls cells. Such modifications did not alter action potentials and the main parameters related to contraction, although shortening was slightly acce…

Mediterranean bioconstructions along the Italian coast

2018

Marine bioconstructions are biodiversity-rich, three-dimensional biogenic structures, regulating key ecological functions of benthic ecosystems worldwide. Tropical coral reefs are outstanding for their beauty, diversity and complexity, but analogous types of bioconstructions are also present in temperate seas. The main bioconstructions in the Mediterranean Sea are represented by coralligenous formations, vermetid reefs, deep-sea cold-water corals, Lithophyllum byssoides trottoirs, coral banks formed by the shallow-water corals Cladocora caespitosa or Astroides calycularis, and sabellariid or serpulid worm reefs. Bioconstructions change the morphological and chemicophysical features of prima…

Edictum Hadriani de re olearia

2013

Epistula Hadriani de re piscatoria

2013

Crocifisso

2010

Cytomegalovirus and BK-Virus co-infection of a clinically non-functioning adrenal adenoma: innocent bystanders or new pathogenetic agents?

2006

We report a case of a 64-year-old woman who underwent left adrenalectomy with removal of a 8,5 cm clinically non-functioning adrenocortical adenoma and a 4-cm myelolipoma. Molecular testing for viral infection demonstrated the presence of cytomegalovirus (CMV) DNA sequences in the adrenal adenoma, but not in the myelolipoma (confirmed by immunohistochemistry). Moreover, the adrenal adenoma was also positive for parvovirus B19, and both adrenal tumor samples were positive for polyomavirus BK (BKV) and adenovirus DNA sequences. This is the first report of co-infection of an adrenocortical adenoma by CMV and BKV. The role of these viruses in adrenal tumorigenesis was postulated.

L'USO DELLE METAFORE IN ADR

2016

Il contributo analizza il ruolo che la metafora può̀ assumere tra le strategie comunicative dei partecipanti a una mediazione, definita dal capo 1, lett. a), D.Lgs. n. 28/2010 come l’attività “svolta da un terzo imparziale e finalizzata ad assistere due o più̀ soggetti nella ricerca di un accordo amichevole per la composizione di una controversia, anche con formulazione di una proposta per la risoluzione della stessa”. L’analisi prende in considerazione i recenti contributi di alcuni studiosi anglo-americani – Haynes 1999; Smith 2003, 2004, 2005, 2009; Chmielecki 2013; Ebbesson 1988, 2008 – sull’uso e sull’utilità̀ delle metafore concettuali nei sistemi di ADR. Il contributo mostra le diver…

Alpha 1 adrenoceptor expression in skin, nerves and blood vessels of patients with painful diabetic neuropathy

2021

Abstract Diabetic neuropathy (dNP) patients often suffer from severe neuropathic pain. It was suggested that alpha-1 adrenoceptor (α1-AR) hyperresponsiveness contributes to pain in dNP. The aim of our study was to quantify α1-AR expression using immunohistochemistry in skin biopsies of nine patients with painful diabetic neuropathy compared to 10 healthy controls. Additionally, the association between α1-AR expression and activation with spontaneous and sympathetically maintained pain (SMP) induced by intradermal injection of the α1-agonist phenylephrine was investigated. For control purposes the α2-agonist clonidine was injected in a different session. We found that dermal nerve density wa…

Neuroendocrine responses in neonatal mother-deprived rabbits.

2009

To study both short- and long-term adaptation mechanisms activated by rabbits which were separated from their mothers (DLS) for 48 h between postnatal days 9 and 11, we examined plasma corticosterone concentrations before, during, and after DLS as well as the expression of glucocorticoid receptor (GR) in the hippocampus and the adrenal axis responses to a mild stress stimuli or exogenous ACTH injection. At postnatal day 10, plasma corticosterone concentration of DLS rabbits was similar to that of controls, but rose two-fold at day 11 (17.7 + or - 1.3 vs. 9.3 + or - 1.2 microg/dl, P0.01) and then decreased at day 12, when suckling was allowed again, to match those of controls with no differe…

THE USE AND THE SHIFT OF METAPHORS IN ADR

2014

This study on the use and shift of metaphors in alternative dispute resolutions aims to consider the clever use of conceptual metaphors among the linguistic competences that are desirable for mediators working in Europe under the provisions of the Directive 2008/52. The interest in developing the role of metaphors in influencing the resolution of disputes has called for a multidisciplinary approach that will focus on the studies carried out by experts in Cognitive Linguistics, Legal Pragmatics, Law and Mediation matters. Part I presents the claims made by Cognitive Linguistics on what a conceptual metaphor is and how it works in both every day and specialized language; Part II deals with th…