Search results for " APN"

showing 10 items of 279 documents

Pulmonary haemodynamics in obstructive sleep apnoea.

1995

In patients with obstructive sleep apnoea syndrome (OSAS), pulmonary haemodynamics can show both transient perturbations during sleep and permanent alterations. During sleep, repeated fluctuations in pulmonary artery pressure and pulmonary wedge pressure, coincident with apnoeas, can be observed. Calculation of transmural pressure values is preferable to intravascular pressures in OSAS, due to the marked swings in intrathoracic pressure associated with obstructive apnoeas. Pulmonary artery pressure may progressively increase during sleep, particularly in close sequences of highly desaturating apnoeas. Apnoea-induced hypoxia appears as the most important determinant of this pulmonary artery …

Cardiac outputPulmonary and Respiratory MedicineCardiac outputmedicine.medical_specialtyHypertension PulmonaryVentricular Dysfunction RightCognitive NeuroscienceSleep REMSettore MED/10 - Malattie Dell'Apparato RespiratorioBehavioral Neurosciencestomatognathic systemPhysiology (medical)Internal medicinemedicine.arteryHumansMedicineRespiratory functionWakefulnessHypoxiaPulmonary wedge pressureLungSleep Apnea Obstructivebusiness.industryHemodynamicsSleep apneaGeneral MedicineStroke volumeHypoxia (medical)medicine.diseasePulmonary artery pressurePulmonary hypertensionnervous system diseasesrespiratory tract diseasesObstructive sleep apneaOphthalmologyStroke volumemedicine.anatomical_structureNeurologyObstructive sleep apnoeaVentricleAnesthesiaPulmonary arteryDentistry (all)CardiologyRight ventricleNeurology (clinical)medicine.symptombusinessJournal of sleep research
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Infantile Central Sleep Apnea - Improvement With Acetazolamide

1999

Central sleep apneabusiness.industryAnesthesiaPediatrics Perinatology and Child HealthMedicinebusinessmedicine.diseaseAcetazolamidemedicine.drugPediatric Research
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Sleep disordered breathing in medically stable patients with myasthenia gravis

2007

We investigate sleep and breathing in clinically stable myasthenia gravis (MG) patients and ask weather sleep disordered breathing (SDB) is causally linked with MG. Nineteen MG patients with a mean disease duration of 9.7 years underwent sleep studies in two consecutive nights. The primary outcome measure was the respiratory disturbance index (RDI) in terms of snoring and apneas/hypopneas. Further outcome measurements were total sleep time, sleep stage distribution and the number of arousals. A clinically relevant SDB in terms of obstructive sleep apnea (OSA) (defined as RDI > 10/h) was found in four patients. There were only a few central apneas (central apnea index: 0.19 +/- 0.4/h). We di…

Central sleep apneabusiness.industryCentral apneaSleep apneamedicine.diseaseSleep in non-human animalsMyasthenia gravisnervous system diseasesrespiratory tract diseasesObstructive sleep apneaNeurologySleep and breathingAnesthesiaRespiratory disturbance indexMedicineNeurology (clinical)businessEuropean Journal of Neurology
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Effects of adenotonsillectomy on neurocognitive and behavioural function in pediatric obstructive sleep apnea syndrome

2018

Effects of adenotonsillectomy on neurocognitive and behavioural function in pediatric obstructive sleep apnea syndrome. Objectives: Aim of this study is to verify the presence of neurocognitive, neurobehavioral or sleep disturbances in children affected by adenotonsillar hypertrophy (ATH) and Obstructive Sleep Apnea Syndrome (OSAS) and verify their improvement after Adeno-Tonsillectomy (AT). Methods: Eighty children suffering from adenotonsillar hypertrophy and OSAS were recruited for AT in the ENT Department of the University of Palermo. All the children underwent clinical evaluation, including rhinofibroscopy for grading the obstruction due to the adenotonsillar hypertrophy (before and 6 …

Children's behavioral disturbanceAdenotonsillar hypertrophyKey-words. sleep breathing disorderOtorhinolaryngology2734 Pathology and Forensic MedicineObstructive sleep apnea
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Effects of sleep apnea and kidney dysfunction on objective sleep quality in nondialyzed patients with chronic kidney disease: an ESADA study

2020

Study Objectives: Patients with chronic kidney disease (CKD) often report poor sleep quality, but they commonly exhibit OSA. The aim of this study was to evaluate the influence of OSA severity and of estimated glomerular filtration rate impairment on objective sleep quality in nondialyzed patients with CKD, defined as an estimated glomerular filtration rate <60 mL/min/1.73m2. Methods: Polysomnographic sleep characteristics were compared between patients with (n = 430) and without CKD (n = 6,639) in the European Sleep Apnea Database cohort. Comparisons were repeated in 375 patients with CKD and 375 control patients without CKD matched for sleep center, age, sex, and AHI, and in 310 matche…

Chronic kidney disease ; Estimated glomerular filtration rate ; Sleep apnea ; Sleep qualitysleep quality.Pulmonary and Respiratory Medicinemedicine.medical_specialtyRenal functionSettore MED/10 - Malattie Dell'Apparato RespiratorioKidneyurologic and male genital diseases03 medical and health sciencesSleep Apnea Syndromes0302 clinical medicinestomatognathic systemChronic kidney diseaseInternal medicineHumansMedicineEstimated glomerular filtration rateRenal Insufficiency ChronicSleep Apnea ObstructiveSleep qualitybusiness.industrySleep apneaKidney dysfunctionSleep apneaSleep qualitymedicine.diseaseScientific Investigationsfemale genital diseases and pregnancy complicationsnervous system diseasesrespiratory tract diseasesPoor sleep030228 respiratory systemNeurologyHuman medicineNeurology (clinical)Sleepbusiness030217 neurology & neurosurgeryKidney diseaseJournal of Clinical Sleep Medicine
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Impact of temperature on obstructive sleep apnoea in three different climate zones of Europe: Data from the European Sleep Apnoea Database (ESADA)

2021

Recent studies indicate that ambient temperature may modulate obstructive sleep apnoea (OSA) severity. However, study results are contradictory warranting more investigation in this field. We analysed 19,293 patients of the European Sleep Apnoea Database (ESADA) cohort with restriction to the three predominant climate zones according to the Koppen-Geiger climate classification: Cfb (warm temperature, fully humid, warm summer), Csa (warm temperature, summer dry, hot summer), and Dfb (snow, fully humid, warm summer). Average outside temperature values were obtained and several hierarchical regression analyses were performed to investigate the impact of temperature on the apnea-hypopnea index …

Cognitive NeuroscienceSettore MED/10 - Malattie Dell'Apparato RespiratorioEnvironmentcomputer.software_genreBody Mass IndexCohort Studies03 medical and health sciencesBehavioral NeuroscienceSleep Apnea SyndromeSleep Apnea Syndromes0302 clinical medicineEnvironmental temperaturestomatognathic systemHumansMedicineOxygen saturation (medicine)Climate zonesSleep Apnea ObstructiveOxygen desaturationDatabasebusiness.industryTemperatureSleep Apnea Obstructive.General MedicineSleep in non-human animalsSleep-related breathing disordersnervous system diseasesrespiratory tract diseasesClinical neurologysleep&#8208030228 respiratory systemClimate zonerelated breathing disorderssleep-related breathing disorderHuman medicineCohort StudiebusinessBody mass indexcomputer030217 neurology & neurosurgeryHumanJournal of Sleep Research
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Respiratory support techniques to avoid desaturation in critically ill patients requiring endotracheal intubation: A systematic review and meta-analy…

2017

Abstract Purpose To evaluate which respiratory support method for critically ill patients undergoing endotracheal intubation (ETI) is associated with less desaturation. Methods We searched PubMed, Cochrane Library, Scopus and CINAHL databases. We included randomized (RCT) and non-randomized (non-RCT) studies investigating any method of respiratory support before/during ETI compared to a reference control. Results Apneic oxygenation (ApOx) was the most commonly investigated respiratory support technique for critically ill patients undergoing intubation (4 RCTs, 358 patients). Three of these studies investigated high-flow nasal cannula (HFNC) for ApOx while standard nasal cannula was used in …

Critical CareDatabases Factualmedicine.medical_treatmentAirway management; Apneic oxygenation; Endotracheal intubation; Noninvasive ventilation; Oxygen inhalation therapy; PreoxygenationCritical IllnessSettore MED/41 - AnestesiologiaEndotracheal intubationAirway managementCochrane LibraryCritical Care and Intensive Care Medicinemedicine.disease_causelaw.invention03 medical and health sciences0302 clinical medicineApneic oxygenationRandomized controlled triallawPreoxygenationmedicineIntubation IntratrachealIntubationCannulaHumansMED/41 - ANESTESIOLOGIAHypoxiabusiness.industryOxygen inhalation therapy030208 emergency & critical care medicineEndotracheal intubationRespiration ArtificialIntubation procedure030228 respiratory systemMeta-analysisAnesthesiaCritical IllneAirway managementbusinessRespiratory InsufficiencyNasal cannulaNoninvasive ventilationHuman
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Medico-legal implications of sleep apnoea syndrome: driving license regulations in Europe.

2008

Background: Sleep apnoea syndrome (SAS), one of the main medical causes of excessive daytime sleepiness, has been shown to be a risk factor for traffic accidents. Treating SAS results in a normalized rate of traffic accidents. As part of the COST Action B-26, we looked at driving license regulations, and especially at its medical aspects in the European region. Methods: We obtained data from Transport Authorities in 25 countries (Austria, AT; Belgium, BE; Czech Republic, CZ; Denmark, DK; Estonia, EE; Finland, FI; France, FR; Germany, DE; Greece, GR; Hungary, HU; Ireland, IE; Italy, IT; Lithuania, LT; Luxembourg, LU; Malta, MT; Netherlands, NL; Norway, EC; Poland, PL; Portugal, PT; Slovakia,…

Cross-Cultural Comparisonmedicine.medical_specialtyPediatricsAutomobile DrivingSleep ApneaDriving license regulationsExcessive daytime sleepinessPoison controlDisorders of Excessive SomnolenceSettore MED/10 - Malattie Dell'Apparato RespiratorioOccupational safety and healthRisk FactorsInjury preventionmedicineHumansPsychiatryLicenseSleep Apnea ObstructiveTraffic/legislation & jurisprudencebusiness.industryAccidents TrafficSleep apneaDisorders of Excessive Somnolence/complicationsGeneral MedicineSleep Apnea Obstructive/complicationsmedicine.diseaseEuropeObstructive sleep apnoeaAccidents Traffic/legislation & jurisprudenceAccidentsCost action sleep apneaMedical certificateObstructive/complicationsmedicine.symptombusinessAutomobile Driving/legislation & jurisprudenceNarcolepsySleep medicine
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Anti-inflammatory medications for the treatment of pediatric obstructive sleep apnea

2020

CyclopropanesPulmonary and Respiratory Medicinemedicine.medical_specialtyAdolescentmedicine.drug_classAnti-Inflammatory AgentsAdministration OralAcetatesSulfidesAnti-inflammatorylaw.inventionRandomized controlled trialAdrenal Cortex HormoneslawInternal medicinemedicineHumansChildAdministration IntranasalMontelukastSleep Apnea Obstructivebusiness.industryInfantmedicine.diseaseObstructive sleep apneaTreatment OutcomeChild PreschoolPediatrics Perinatology and Child HealthQuinolinesLeukotriene Antagonistsbusinessmedicine.drugPaediatric Respiratory Reviews
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Change in weight and central obesity by positive airway pressure treatment in obstructive sleep apnea patients: longitudinal data from the ESADA coho…

2018

The effect of positive airway pressure treatment on weight and markers of central obesity in patients with obstructive sleep apnea remains unclear. We studied the change in body weight and anthropometric measures following positive airway pressure treatment in a large clinical cohort. Patients with obstructive sleep apnea with positive airway pressure treatment from the European Sleep Apnea Database registry (n = 1, 415, 77% male, age 54 ± 11 [mean ± SD] years, body mass index 31.7 ± 6.4 kg/m2, apnea–hypopnea index 37 ± 24 n per hr, Epworth Sleepiness Scale 10.2 ± 5.0) were selected. Changes in body mass index and neck/waist/hip circumferences at baseline and at follow-up visit were analyse…

Data AnalysisMaleTime FactorsExcessive daytime sleepinessWeight Gainexcessive daytime sleepineBody Mass IndexCohort StudiesBehavioral Neuroscience0302 clinical medicinePositive airway pressureMedicineLongitudinal StudiesProspective Studiesobstructive sleep apneaSleep Apnea ObstructiveContinuous Positive Airway PressureEpworth Sleepiness ScaleSleep apneaGeneral MedicineMiddle Agedweight ; central obesity ; positive airway pressure ; obstructive sleep apnea ; ESADA cohortEuropeObesity AbdominalCardiologyFemaleWaist Circumferencemedicine.symptomAdultmedicine.medical_specialtyCognitive NeuroscienceSettore MED/10 - Malattie Dell'Apparato Respiratorio03 medical and health sciencesInternal medicineHumanspositive airway pressureAgedcentral obesitybusiness.industryBody Weightbody weight central obesity excessive daytime sleepiness obstructive sleep apnea positive airway pressureta3121medicine.diseaseObesityrespiratory tract diseasesObstructive sleep apnea030228 respiratory systemHuman medicinebusinessBody mass indexWeight gain030217 neurology & neurosurgery
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