Search results for " ARCHITECTURE."

showing 10 items of 2517 documents

Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease

2020

Abstract Background Advanced age-related macular degeneration (AMD) is a leading cause of blindness. While around half of the genetic contribution to advanced AMD has been uncovered, little is known about the genetic architecture of early AMD. Methods To identify genetic factors for early AMD, we conducted a genome-wide association study (GWAS) meta-analysis (14,034 cases, 91,214 controls, 11 sources of data including the International AMD Genomics Consortium, IAMDGC, and UK Biobank, UKBB). We ascertained early AMD via color fundus photographs by manual grading for 10 sources and via an automated machine learning approach for > 170,000 photographs from UKBB. We searched for early AMD loc…

0301 basic medicinegenetic structures610 MedizinGenome-wide association studyMacular Degeneration0302 clinical medicineAdvanced diseaseCD46Genetics (clinical)GeneticsInternational AMD genomics consortium (IAMDGC)ddc:6100303 health sciencesGenome-wide association study (GWAS)3. Good health030220 oncology & carcinogenesisAge-related macular degeneration (AMD)Meta-analysisResearch ArticleGenetic Markerslcsh:Internal medicineUK biobank (UKBB)lcsh:QH426-470Locus (genetics)GenomicsComputational biologyBiologyPolymorphism Single NucleotideGenome-wide association study (GWAS) Meta-analysis Age-related macular degeneration (AMD) Early AMD CD46 TYR International AMD genomics consortium (IAMDGC) UK biobank (UKBB) Machine-learning Automated phenotyping03 medical and health sciencesEarly AMDGeneticsmedicineHumansGenetic Predisposition to DiseaseGenome-wide Association Study (gwas) ; Meta-analysis ; Age-related Macular Degeneration (amd) ; Early Amd ; Cd46 ; Tyr ; International Amd Genomics Consortium (iamdgc) ; Uk Biobank (ukbb) ; Machine-learning ; Automated Phenotypinglcsh:RC31-1245Machine-learning030304 developmental biologyTYRCD46Macular degenerationmedicine.diseaseHuman geneticseye diseasesGenetic architectureMeta-analysislcsh:Genetics030104 developmental biologyGenetic LociCase-Control StudiesAutomated phenotypingHTRA1030221 ophthalmology & optometrysense organsGenome-Wide Association Study
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The effect of visual motion stimulus characteristics on vection and visually induced motion sickness

2019

Abstract Several factors contribute to the likelihood of experiencing illusory sensations of self-motion (i.e., vection) in Virtual Reality (VR) applications. VR users can also experience adverse effects such as disorientation, oculomotor issues, or nausea known as visually induced motion sickness (VIMS). The goal of the present study was to systematically investigate three characteristics of visual motion stimuli—speed, density, and axis of rotation—and how they relate to both vection and VIMS. Two experiments were conducted. In Experiment 1, a stereoscopic stimulus containing a star field of white spheres on a black background was presented to 21 participants. The stimulus contained linea…

030110 physiology0301 basic medicinemedicine.medical_specialtyStimulus (physiology)Audiologymedicine.diseasehumanitiesVisual motionHuman-Computer Interaction03 medical and health sciences0302 clinical medicineMotion sicknessHardware and ArchitectureSensationmedicineElectrical and Electronic EngineeringCurvilinear motion030217 neurology & neurosurgeryMathematicsDisplays
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Building an Optimal WSD Ensemble Using Per-Word Selection of Best System

2006

In Senseval workshops for evaluating WSD systems [1,4,9], no one system or system type (classifier algorithm, type of system ensemble, extracted feature set, lexical knowledge source etc.) has been discovered that resolves all ambiguous words into their senses in a superior way. This paper presents a novel method for selecting the best system for target word based on readily available word features (number of senses, average amount of training per sense, dominant sense ratio). Applied to Senseval-3 and Senseval-2 English lexical sample state-of-art systems, a net gain of approximately 2.5 – 5.0% (respectively) in average precision per word over the best base system is achieved. The method c…

0303 health sciencesWord-sense disambiguationComputer scienceSample (material)Speech recognition02 engineering and technologyBase (topology)SemanticsSupport vector machine03 medical and health sciencesPattern recognition (psychology)Classifier (linguistics)0202 electrical engineering electronic engineering information engineering020201 artificial intelligence & image processingWord (computer architecture)030304 developmental biology
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Multifunctional Bioinstructive 3D Architectures to Modulate Cellular Behavior

2019

Biological structures control cell behavior via physical, chemical, electrical, and mechanical cues. Approaches that allow us to build devices that mimic these cues in a combinatorial way are lacking due to there being no suitable instructive materials and limited manufacturing procedures. This challenge is addressed by developing a new conductive composite material, allowing for the fabrication of 3D biomimetic structures in a single manufacturing method based on two?photon polymerization. The approach induces a combinatorial biostimulative input that can be tailored to a specific application. Development of the 3D architecture is performed with a chemically actuating photocurable acrylate…

0303 health sciencesbiomimetic 3D architecturesMaterials scienceregenerative medicineNanotechnology02 engineering and technology3D printing021001 nanoscience & nanotechnologyCondensed Matter PhysicsRegenerative medicineElectronic Optical and Magnetic Materialscardiomyocyte maturationBiomaterials03 medical and health sciencesGeneral chemical engineeringElectrochemistry0210 nano-technology030304 developmental biologyAdvanced Functional Materials
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A Review of the State-of-the-Art of Assistive Technology for People with ASD in the Workplace and in Everyday Life

2019

Part 8: Digital Divide and Social Inclusion; International audience; Autism, also known as autism spectrum disorder (ASD), is an incurable brain-based disorder that refers to a wide range of complex neurodevelopment disorders characterised by marked difficulties in communication and social skills, repetitive behaviour, highly focused interests and sensory sensitivity. Autism can present challenges for affected people at the work environment and in everyday life. The barrier for individuals with ASD increases further with changing environmental situations. Individuals with ASD have limited abilities to isolate their Five senses and often experience over- or under-sensitivity to sounds, touch…

030506 rehabilitationAutismbehavioral disciplines and activitiesASDDevelopmental psychology03 medical and health sciences[INFO.INFO-NI]Computer Science [cs]/Networking and Internet Architecture [cs.NI]Social skillsAssistive technologymental disordersmedicine0501 psychology and cognitive sciences[INFO]Computer Science [cs]Everyday lifeSensory sensitivity05 social sciencesPerspective (graphical)medicine.diseaseWork environmentAssistive technologyAutism spectrum disorderAutismComputingMilieux_COMPUTERSANDSOCIETY0305 other medical sciencePsychology050104 developmental & child psychology
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Some reflections on semantic–pragmatic cycles

2020

Abstract This paper explores novel ways to consider semantic–pragmatic cycles using a dual strategy: an inwards strategy, whereby the distinctive traits of a pragmatic cycle are established, and an outwards strategy, whereby the categories that delimit semantic–pragmatic cycles are described. The result of this exploration is the distinction between “pragmatic cycle”, “replication”, “concomitance” and “paradigmatic increase” as four different yet related processes. In addition, this study integrates Construction Grammar into the description of each process and shows that the study of semantic–pragmatic cycles can benefit from a constructional approach, adopting Traugott and Trousdale’s (201…

050101 languages & linguisticsLinguistics and LanguageFunctional programmingStructuralism (philosophy of science)Process (engineering)05 social sciencesDiasystem0501 psychology and cognitive sciencesSociologyConstruction grammarDUAL (cognitive architecture)Language and LinguisticsLinguisticsJournal of Historical Pragmatics
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Why Digital Games Can Be Advantageous in Vocabulary Learning

2021

Vocabulary learning is an integral part of language learning; however, it is difficult. Although there are many techniques proposed for vocabulary learning and teaching, researchers still strive to find effective methods. Recently, digital games have shown potentials in enhancing vocabulary acquisition. A majority of studies in digital game-based vocabulary learning (DGBVL) literature investigate the effectiveness of DGBVL tasks. In other words, there are enough answers to what questions in DGBVL literature whereas why questions are rarely answered. Finding such answers help us learn more about the structure of the DGBVL tasks and their effects on vocabulary learning. Hence, to achieve this…

050101 languages & linguisticsLinguistics and LanguageVocabularyComputer sciencemedia_common.quotation_subject0211 other engineering and technologies02 engineering and technologycomputer.software_genrelanguage learningLanguage and LinguisticsInteractivitysanavarastoEncoding (memory)0501 psychology and cognitive sciencessanatword learningkielen oppiminenmedia_commonStructure (mathematical logic)digital game-based learningRepetition (rhetorical device)business.industrydigital game05 social sciences021107 urban & regional planningDUAL (cognitive architecture)Language acquisitionvocabulary learningVocabulary learningArtificial intelligencebusinesscomputerdigitaaliset pelitNatural language processingTheory and Practice in Language Studies
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The Structured Assessment Dialogue

2017

The two key purposes of assessment, formative and summative, are often in a contradictory position if they are used concurrently. The summative assessment of learning will often prevent the formative assessment for learning to be realised (Butler, J Educ Psychol 79(4):474, 1987), meaning that the learning potential of the assessment will often be minimal. It is therefore a central challenge to find ways to combine the dual use of assessment. The structured assessment dialogue (SAD) is a candidate for such a combination.

050101 languages & linguisticsPeer feedback05 social sciences050301 education06 humanities and the artsDUAL (cognitive architecture)Formative assessmentLearning potentialSummative assessmentMathematics education0501 psychology and cognitive sciencesPsychology0503 educationMeaning (linguistics)
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Drone arc routing problems

2018

[EN] In this article, we present some drone arc routing problems (Drone ARPs) and study their relation with well-known postman ARPs. Applications for Drone ARPs include traffic monitoring by flying over roadways, infrastructure inspection such as by flying along power transmission lines, pipelines or fences, and surveillance along linear features such as coastlines or territorial borders. Unlike the postmen in traditional ARPs, drones can travel directly between any two points in the plane without following the edges of the network. As a consequence, a drone route may service only part of an edge, with multiple routes being used to cover the entire edge. Thus the Drone ARPs are continuous o…

050210 logistics & transportation021103 operations researchComputer Networks and Communicationsbusiness.industry05 social sciences0211 other engineering and technologiesEuropean Regional Development Fund02 engineering and technologyDroneRural postman problemHardware and ArchitecturePolitical science0502 economics and businessCutting path problemsTelecommunicationsbusinessMATEMATICA APLICADAArc routingSoftwareInformation SystemsDrones
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School Bike Sharing Program: will it Succeed?

2020

Abstract Encouraging active and sustainable transport modes in order to limit the excessive use of cars, as well as reducing pollutant emissions and creating livable urban environments, has become one of the priorities for policymakers in recent years. The introduction of innovative systems increasingly being introduced in modern cities, such as bike sharing, can certainly contribute to the spread of cycling and thus allow a radical change in the mobility habits of their citizens. This can be especially true for high-school students who are often otherwise accompanied by their parents with private cars. This article aims to assess the influence that a bike sharing program for students has o…

050210 logistics & transportation05 social sciencesbike sharing shared mobility transport demand0211 other engineering and technologiesPoison control02 engineering and technologySuicide preventionModalSustainable transportOrder (exchange)021105 building & construction0502 economics and businessTRIPS architectureBusinessMarketingCyclingMultinomial logistic regressionTransportation Research Procedia
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