Search results for " ASSOCIATION"

Role of PTPRJ genotype in papillary thyroid carcinoma risk

2010

The strong genetic predisposition to papillary thyroid carcinoma (PTC) might be due to a combination of low-penetrance susceptibility variants. Thus, the research into gene variants involved in the increase of susceptibility to PTC is a relevant field of investigation. The gene coding for the receptor-type tyrosine phosphatase PTPRJ has been proposed as a cancer susceptibility gene, and its role as a tumor suppressor gene is well established in thyroid carcinogenesis. In this study, we want to ascertain the role of PTPRJ genotype in the risk for PTC. We performed a case–control study in which we determined the PTPRJ genotype for the non-synonymous Gln276Pro and Asp872Glu polymorphisms by PC…

Updated Field Synopsis and Systematic Meta-Analyses of Genetic Association Studies in Cutaneous Melanoma: The MelGene Database

2015

We updated a field synopsis of genetic associations of cutaneous melanoma (CM) by systematically retrieving and combining data from all studies in the field published as of August 31, 2013. Data were available from 197 studies, which included 83,343 CM cases and 187,809 controls and reported on 1,126 polymorphisms in 289 different genes. Random-effects meta-analyses of 81 eligible polymorphisms evaluated in4 data sets confirmed 20 single-nucleotide polymorphisms across 10 loci (TYR, AFG3L1P, CDK10, MYH7B, SLC45A2, MTAP, ATM, CLPTM1L, FTO, and CASP8) that have previously been published with genome-wide significant evidence for association (P5 × 10(-8)) with CM risk, with certain variants pos…

Large-scale genome-wide association studies on a GPU cluster using a CUDA-accelerated PGAS programming model

2015

[Abstract] Detecting epistasis, such as 2-SNP interactions, in genome-wide association studies (GWAS) is an important but time consuming operation. Consequently, GPUs have already been used to accelerate these studies, reducing the runtime for moderately-sized datasets to less than 1 hour. However, single-GPU approaches cannot perform large-scale GWAS in reasonable time. In this work we present multiEpistSearch, a tool to detect epistasis that works on GPU clusters. While CUDA is used for parallelization within each GPU, the workload distribution among GPUs is performed with Unified Parallel C++ (UPC++), a novel extension of C++ that follows the Partitioned Global Address Space (PGAS) model…

Geographically representative scholarship and internationalization in school and educational psychology: A bibliometric analysis of eight journals fr…

2018

Abstract Although the discipline of school and educational psychology is arguably international (e.g., relevant research and practice is evident in more than 80 countries), there has been limited research examining the international scholarship published in school and educational psychology journals. Such an assessment is important because it provides one important metric for better understanding the field's level of internationalization. The purpose of this study was to evaluate every article (N = 4456) published from 2002 to 2016 across eight school and educational psychology journals that publish international scholarship. Each article's authorship and participant data were coded and rep…

Interference of left and right cerebellar rTMS with procedural learning.

2004

Abstract Increasing evidence suggests cerebellar involvement in procedural learning. To further analyze its role and to assess whether it has a lateralized influence, in the present study we used a repetitive transcranial magnetic stimulation interference approach in a group of normal subjects performing a serial reaction time task. We studied 36 normal volunteers: 13 subjects underwent repetitive transcranial magnetic stimulation on the left cerebellum and performed the task with the right (6 subjects) or left (7 subjects) hand; 10 subjects underwent repetitive transcranial magnetic stimulation on the right cerebellum and performed the task with the hand ipsilateral (5 subjects) or contral…

OPTIMA Newsletter

2016

OPTIMA Newsletter is a news journal for the presentation and discussion of issues pertinent to Mediterranean botany, published by the Secretariat of the Organization for the Phyto-Taxonomic Investigation of the Mediterranean Area.

Equilibrium/steady-state concept in phytoplankton ecology

2003

This paper summarises the outcomes of the 13th Workshop of the International Association of Phytoplankton Taxonomy and Ecology (IAP). The authors mostly addressed their contributions on the following topics: the effect of trophic state on the attainment of a steady-state; the establishment of equilibria in deep and shallow lakes; the role of spatial heterogeneity, disturbance, and stress in the establishment of equilibrium assemblages; the mechanisms leading to the steady state; the frequency and longevity of equilibrium phases, and the role of morphological and physiological plasticity of phytoplankton in maintaining the (apparently) same populations under different environmental condition…

Comparative Phylogenomic Data on Primates through Chromosomal Painting

2009

A Data Association Algorithm for People Re-Identification in Photo Sequences

2010

In this paper, a new system is presented to support the user in the face annotation task. Every time a photo sequence becomes available, the system analyses it to detect and cluster faces in set corresponding to the same person. We propose to model the problem of people re-identification in photos as a data association problem. In this way, the system takes advantage from the assumption that each person can appear at most once in each photo. We propose a fully automated method for grouping facial images, the method does not require any initialization neither a priori knowledge of the number of persons that are in the photo sequence. We compare the results obtained with our method and with s…

An on-line learning method for face association in personal photo collection

2012

Due to the widespread use of cameras, it is very common to collect thousands of personal photos. A proper organization is needed to make the collection usable and to enable an easy photo retrieval. In this paper, we present a method to organize personal photo collections based on ''who'' is in the picture. Our method consists in detecting the faces in the photo sequence and arranging them in groups corresponding to the probable identities. This problem can be conveniently modeled as a multi-target visual tracking where a set of on-line trained classifiers is used to represent the identity models. In contrast to other works where clustering methods are used, our method relies on a probabilis…