Search results for " Addiction"

Acute Nicotine Induces Anxiety and Disrupts Temporal Pattern Organization of Rat Exploratory Behavior in Hole-Board: A Potential Role for the Lateral…

2015

Nicotine is one of the most addictive drugs of abuse. Tobacco smoking is a major cause of many health problems, and is the first preventable cause of death worldwide. Several findings show that nicotine exerts significant aversive as well as the well-known rewarding motivational effects. Less certain is the anatomical substrate that mediates or enables nicotine aversion. Here, we show that acute nicotine induces anxiogenic-like effects in rats at the doses investigated (0.1, 0.5, and 1.0 mg/kg, i.p.), as measured by the hole-board apparatus and manifested in behaviors such as decreased rearing and head-dipping and increased grooming. No changes in locomotor behavior were observed at any of …

Effectiveness of oral health education versus nicotine replacement therapy for tobacco cessation- a parallel randomized clinical trial.

2015

Background: India has millions of tobacco users. It is the leading cause of deaths due to oral cancer and hence needs effective strategies to curb it. Hence the aim of present study was to evaluate and compare the effectiveness of Oral Health Education (OHE) and Nicotine Replacement Therapy (NRT) in tobacco cessation. Material and Methods: The clinical trial consisted of Manohar Lal Kapoor (MLK) factory workers (n= 40) giving history of tobacco consumption (smoking/smokeless) within past 30 days. They were randomized into OHE (n=20) and NRT (n=20) groups. Baseline evaluation (demographic, smoking/ smokeless behaviour) was done. Fagerstrom test was used for Nicotine Dependence (FTND) and to …

Internet addiction, temperament, and the moderator role of family emotional involvement

2014

This study examined the relationship between internet addiction, temperament, and family functioning focusing on the unique and common contribution that temperament and family functioning made to internet addiction. A total of 320 adolescents (164 boys and 156 girls), from 15 to 17 years (M = 16.06, SD = 0.59), completed measures of internet addiction, temperament, and family functioning. Data showed that salience, as the ability of internet to change negatively person’s life, was predicted positively by temperament linked to lack of control and by the perception of low level of familial emotional involvement. Results also revealed that family affective involvement played a moderating role …

2021

IntroductionIn May 2019, the WHO classified internet gaming disorder (IGD) as a mental disorder in the upcoming International Classification of Diseases 11th Revision. However, individuals affected by IGD or internet use disorders (IUDs) are often not provided with adequate therapy due to a lack of motivation or absence of adequate local treatment options. To close the gap between individuals with IUDs and the care system, we conduct an online-based motivational intervention to reduce problematic internet use and promote treatment motivation in internet gaming disorder and internet use disorder (OMPRIS).Methods and analysisWithin the randomised controlled trial, a total of n=162 participant…

Therapies in early development for the treatment of opiate addiction.

2015

Opiate drugs are psychoactive substances used to manage severe pain. However, their chronic use is associated with the development of addiction. Opiate addiction represents a significant public health concern.This review focuses on the most recent advances in the pharmacological treatment of opiate addiction, from those being tested in clinical trials (Phase I and II), to preclinical studies that point to new targets. Readers will gain knowledge of the wide variety of treatments used to treat opiate addiction, including their strengths and weaknesses, and the promising pharmacological targets identified by preclinical research.Among the currently available agonist therapies, new dosage form…

Online gambling: A treatment for sports betting addiction

2020

Resumen Antecedentes : el juego de azar online (apuestas, juegos de casino, póquer, etc.) es una actividad que se está extendiendo mundialmente, incluso en los países en los cuales todavía no está legalizado. A pesar de que la situación en Latinoamérica es de lo más diversa, es probable que conforme se desarrolle y promocione el juego online aparezcan problemas de adicción, de forma similar a lo que está ocurriendo en España desde que este tipo de juegos se legalizó en 2011. De manera que la ciencia psicológica debe ir desarrollando programas de tratamiento que hagan frente a la nueva realidad. Objetivo: el artículo presenta el procedimiento seguido para el tratamiento de un joven con probl…

Problematic Internet Use and Resilience: A Systematic Review and Meta-Analysis

2023

Problematic Internet use has become a major problem worldwide due to its numerous negative correlates in the field of health, both mental and physical, and its increasing prevalence, making it necessary to study both its risk and protective factors. Several studies have found a negative relationship between resilience and problematic Internet use, although the results are inconsistent. This meta-analysis assesses the relationship between problematic Internet use and resilience, and analyses its possible moderating variables. A systematic search was conducted in PsycInfo, Web of Science and Scopus. A total of 93,859 subjects from 19 studies were included in the analyses. The results show tha…

Musikkterapi for mennesker med rusmiddelproblematikk: En kvalitativ metasyntese om erfaringer og opplevelser

2018

Masteroppgave klinisk helsevitenskap ME520 - Universitetet i Agder 2018 Background: Music therapy and other music-based therapies have become common in Norwegian mental health and drug misuse treatments in recent years. There are studies indicating that music therapy has good effect on this patient group. There is recommendation from the Norwegian Directorate of Health that music therapy should be offered in drug rehabilitation programs. However, little research exists on how people with substance abuse problems experience this form of therapy. Aim: This study aims to compare existing research of the experiences of people with substance abuse problems with music therapy. Research-question: …

Nicotinic receptor agonists as neuroprotective/neurotrophic drugs. Progress in molecular mechanisms

2007

In the present work we reviewed recent advances concerning neuroprotective/neurotrophic effects of acute or chronic nicotine exposure, and the signalling pathways mediating these effects, including mechanisms implicated in nicotine addiction and nAChR desensitization. Experimental and clinical data largely indicate long-lasting effects of nicotine and nicotinic agonists that imply a neuroprotective/neurotrophic role of nAChR activation, involving mainly alpha 7 and alpha 4 beta 2 nAChR subtypes, as evidenced using selective nAChR agonists. Compounds interacting with neuronal nAChRs have the potential to be neuroprotective and treatment with nAChR agonists elicits long-lasting neurotrophic e…

Four essays on IT users' psychological states and behaviors

2016

This dissertation is intended to study information technology (IT) users’ psychological states and behaviors. It consists of four essays. The first essay examines how people react to social networking services (SNS). In this essay, we attempted to extend the existing model, which includes dedication- and constraint-based mechanisms, by additionally including the obligation-based mechanism underlying SNS-related behavior. The second essay is designed to investigate individuals’ smartphone use. In particular, we focused on the role of smartphone addiction in shaping individuals’ perceptions about their smartphone. The third essay is about online community behavior. Drawing on the model of eng…