Search results for " Administration"
showing 10 items of 4299 documents
Ernährung bei Patienten mit Kopf-Hals-Tumoren
2005
Nutrition in Patients with Head and Neck Cancer. Malnutrition is common in patients with head and neck cancer. Due to natural course of disease or therapy, malnutrition may increase. This leads to a reduced prognosis, quality of life, and should be considered in early stages of the disease. First choice is an enteral feeding via a nasogastral feeding tube or a PEG. In special cases a parenteral nutrition may be necessary.
The value of Ems Mineral Salts in the treatment of rhinosinusitis in children
2005
Summary The treatment of rhinosinusitis seen in the light of uncertain pathogenesis and variable symptoms is under discussion and ranges from the administration of antibiotics, decongestants and anti-allergic agents to no treatment. In this randomized, prospective, double-blind and controlled study the effect of a 14-day treatment (1–2 sprays into each nostril t.d.) with either isotonic Ems Mineral Salts (EMS) solution (Siemens & Co., Bad Ems, Germany) or xylometazoline solution (0.05%) was tested in children (n = 66) aged 2–6 years. Main outcomes: the degree of mucosal inflammation, nasal patency, general state of health, condition of the middle ear, auditory function as well as an assessm…
Eine Mannitollösung als orales Kontrastmittel in der pelvinen MRT
1995
PURPOSE Improvement of pelvic MRI using peroral administration of an aqueous mannitol solution. METHODS We retrospectively evaluated magnetic resonance examinations of 72 patients with suspected or proven pelvic abnormalities: In 36 patients, no bowel marking was carried out. In further 36 patients, we performed a contrast enhancement of the bowel by oral application of 1000 ml of an aqueous mannitol solution. RESULTS 8/36 (22%) patients suffered from diarrhoea, nausea or meteorism as a result of mannitol application. In group 2, an excellent bowel marking of the small intestine could be obtained in 36/36 (100%) patients. Contrast enhancement of the bowel significantly improved delineation …
Restoration of cerebral and systemic microvascular architecture in APP/PS1 transgenic mice following treatment with Liraglutide™.
2015
OBJECTIVE: Cerebral microvascular impairments occurring in AD may reduce Aβ peptide clearance and impact upon circulatory ultrastructure and function. We hypothesized that microvascular pathologies occur in organs responsible for systemic Aβ peptide clearance in a model of AD and that Liraglutide (Victoza(®)) improves vessel architecture. METHODS: Seven-month-old APP/PS1 and age-matched wild-type mice received once-daily intraperitoneal injections of either Liraglutide or saline (n = 4 per group) for eight weeks. Casts of cerebral, splenic, hepatic, and renal microanatomy were analyzed using SEM. RESULTS: Casts from wild-type mice showed regularly spaced microvasculature with smooth lumenal…
The Rockefeller Foundation and the League of Nations: Public Health in Europe (1920-1945)
2021
The Rockefeller Foundation (RF) and the League of Nations (LON) played a fundamental role in stabilization policies during the interwar period. Public health became essential in this context due to the immediate consequences of the war, the post-war economic crisis and the Great Depression. RF and LON became the cornerstone of international action in several fields: epidemics, famine, malnutrition, infectious diseases, infant mortality, drug abuse, biological and dietary standard-setting, epidemiological records, public health policies and professionalization. In the shaping international health expertise, LON and RF collaboration was extremely important, in terms of determining goals and p…
Public Health Policy to Tackle Social Health Inequalities: A Balancing Act Between Competing Institutional Logics
2020
Kvale and colleagues examine the logics of Norwegian government initiatives to respond to social inequalities in health. Whereas the individualist logic favors bounded and specialized measures and organization, the collectivist logic favors broad approaches and organizational coordination. A content analysis of Norwegian health policy documents between 2003 and 2017 shows how such specialized and integrative measures and structures are alternately introduced and hence create a pattern of priorities to tackle public health challenges alternating between a collectivist and an individualist logic. They argue that reform of service coordination to tackle social inequalities in health requires a…
Effects of Morning Versus Evening Statin Administration on Lipid Profile: A Systematic Review and Meta-Analysis
2017
Background Evidence about the optimal time of day at which to administer statins is lacking. Objective The objective of this study is to synthesize evidence about effects of morning vs evening statin administration on lipid profile. Methods We searched PubMed, SCOPUS, Web of Science, and Embase databases (from inception up to July 24, 2016) to identify the relevant studies. Mean differences (MDs) between the change scores in lipid parameters were pooled using a fixed-effect model. Results Eleven articles with 1034 participants were eligible for the analysis. The pooled analysis comparing effects of morning vs evening administration of statins on plasma total cholesterol (TC; P = .10), high…
Reducing the initial number of rituximab maintenance-therapy infusions for ANCA-associated vasculitides: randomized-trial post-hoc analysis
2020
AbstractObjectiveThe randomized, controlled MAINRITSAN2 trial was designed to compare the capacity of an individually tailored therapy [randomization day 0 (D0)], with reinfusion only when CD19+ lymphocytes or ANCA had reappeared, or if the latter’s titre rose markedly, with that of five fixed-schedule 500-mg rituximab infusions [D0 + D14, then months (M) 6, 12 and 18] to maintain ANCA-associated vasculitis (AAV) remissions. Relapse rates did not differ at M28. This ancillary study was undertaken to evaluate the effect of omitting the D14 rituximab infusion on AAV relapse rates at M12.MethodsMAINRITSAN2 trial data were subjected to post-hoc analyses of M3, M6, M9 and M12 relapse-free surviv…
Single Preoperative Oral Application of Ascorbic Acid Does Not Affect Postoperative Plasma Levels of Ascorbic Acid
2002
<i>Background and Aims:</i> A decrease in ascorbic acid (AA) plasma concentration is well known during the postoperative period and postulated to be caused by increased radical scavenging activity in response to surgical trauma. This often affects postoperative patients and is associated with multiple organ failure. Therefore, substitution of AA could potentially decrease the risk of postoperative complications. This study examines the effect of preoperative oral administration of 1,000 mg AA on the postoperative AA plasma concentration. <i>Methods:</i> 54 patients were randomly split into two groups; patients in group 1 received no AA preoperatively while group 2 re…
Incidence and factors associated with burnout in anesthesiology: A systematic review
2017
Background. Burnout syndrome has reached epidemic levels among physicians (reported around 50%). Anesthesiology is among the most stressful medical disciplines but there is paucity of literature as compared with others. Analysis of burnout is essential because it is associated with safety and quality of care. We summarize evidence on burnout in anesthesiology. Methods. We conducted a systematic review (MEDLINE up to 30.06.2017). We included studies reporting burnout in anesthesiology with no restriction on role or screening test used. Results. Fifteen surveys/studies described burnout in anesthesiology, including different workers profiles (nurses, residents, consultants, and directors). Al…