Search results for " Adoptive"

Teachers' Representations on Adoptive Families and Educational Practices: New Challenges in Teachers' Preparation

2016

ABSTRACTIn Italy, as in Europe, the number of internationally adopted school-aged children is increasing. The school is the first place where they can meet their new context, enabling good achievement of the whole integration and adoption processes. The research uses a qualitative method to explore the representations and the strategies that guide the educational work of 268 teachers of eight primary schools in relation to the adoptive family. ATLAS.ti 7.0 software was used. The results show an ambivalent representation of the adoptive family, which is reflected in the contents and strategy used by teachers to address issues of adoption.

Enhanced dendritic cell maturation by TNF-alpha or cytidine-phosphate-guanosine DNA drives T cell activation in vitro and therapeutic anti-tumor immu…

2000

Abstract Dendritic cells (DC) manipulated ex vivo can induce tumor immunity in experimental murine tumor models. To improve DC-based tumor vaccination, we studied whether DC maturation affects the T cell-activating potential in vitro and the induction of tumor immunity in vivo. Maturation of murine bone marrow-derived DC was induced by GM-CSF plus IL-4 alone or by further addition of TNF-α or a cytidine-phosphate-guanosine (CpG)-containing oligonucleotide (ODN-1826), which mimics the immunostimulatory effect of bacterial DNA. Flow cytometric analysis of costimulatory molecules and MHC class II showed that DC maturation was stimulated most by ODN-1826, whereas TNF-α had an intermediate effec…

Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells.

2006

AbstractAdoptive transfer of dendritic cells (DCs) transfected with in vitro–transcribed, RNA-encoding, tumor-associated antigens has recently entered clinical testing as a promising approach for cancer immunotherapy. However, pharmacokinetic exploration of RNA as a potential drug compound and a key aspect of clinical development is still pending. While investigating the impact of different structural modifications of RNA molecules on the kinetics of the encoded protein in DCs, we identified components located 3′ of the coding region that contributed to a higher transcript stability and translational efficiency. With the use of quantitative reverse transcription–polymerase chain reaction (R…

L'adozione nel contesto e co-testo scuola. Literature review su adozione-scuola con Atlas.ti

Our research wants to be a meta-analysis work; its purpose is to focus on adoption and to analyse the “textual-semantic correlates” through which this topic has been understood and interpreted by international literature. In particular, the aim is to describe and codify the semantic-linguistic treatment of “adoption of children” theme with reference to school adjustment issue. In the title of the following thesis, “Adoption in the school context and co-text”, the term co-text (stemming from linguistics) points out the inquiry function in texts and the purpose of meta-reflective comparison among texts of articles coming from the journals with a high impact factor. After selecting those journ…

Holden Lori with Hass Crystal: The open-hearted way to open adoption. Helping your child growing up whole

2015

An open adoption is a way of keeping in contact with the biological roots, maybe more suitable for children adopted in their early infancy than later. In fact, children in older adoption age, coming from a pre-adoptive adverse environment (abuse, neglect, violence, poverty, etc.), may invoke oblio right ,tore-create themselves in the new family.

Methodological findings in studies on adoptive families

2014

The issue of adoptive families is the object of interest for many researchers, especially outside Polish borders. A critical analysis of previous studies on adoption shows that the scientific value of many of the existing studies raises doubts. The reasons of this are more or less significant methodological weaknesses, which significantly reduce their scientific value. Researchers often focus on the study of individuals in the adoptive family, e.g. mothers only, adopted children only or selected types of relationships within the family e.g. the mother – child relation. There is a little amount of studies on family systems. It seems worthy to note that numerous studies are conducted in the c…

T-Cell Vaccination in Patients with Nickel Allergic Contact Dermatitis

1995

Effects of B-Cell Lymphoma on the Immune System and Immune Recovery after Treatment: The Paradigm of Targeted Therapy

2022

B-cell lymphoma and lymphoproliferative diseases represent a heterogeneous and complex group of neoplasms that are accompanied by a broad range of immune regulatory disorder phenotypes. Clinical features of autoimmunity, hyperinflammation, immunodeficiency and infection can variously dominate, depending on the immune pathway most involved. Immunological imbalance can play a role in lymphomagenesis, also supporting the progression of the disease, while on the other hand, lymphoma acts on the immune system to weaken immunosurveillance and facilitate immunoevasion. Therefore, the modulation of immunity can have a profound effect on disease progression or resolution, which makes the immune syst…

New trends in teacher’s education. Educational placement of the adopted child

2015

Abstract In Italy, the number of adopted school-age children is increasing. According to the Commission of Intercountry Adoption (2013), 3106 children were adopted, 47.5% of them are between 5 and 9 years old. The present action-research aims at exploring the spread of good approaches in schools in terms of welcoming of adopted children. For this purpose, 268 teachers of primary schools were involved in analyzing the social representation about adopted children and their family. The results show a simplified vision of the adoptive family, which is described as heroic family or, on the contrary, as a family with difficulty.

Editorial: Understanding Gamma Delta T Cell Multifunctionality - Towards Immunotherapeutic Applications.

2020

Introduction: gd T cells have been characterized by the expression of a gd T cell receptor (TCR).When the gd TCR and the corresponding ab TCR were first discovered it was assumed that the corresponding cell types were likely to be functionally very similar. However, some 30 years later, we have realized that they are not. Unlike ab T cells, gd T cells (i) sense target antigens independent of MHC molecules; (ii) display NK-cell like innate reactivities, including killing of infected cells as well as microbes; (iii) are able to take up large particulates, including bacteria, and (iv) can act as professional antigen presenting cells. The “stress sensing” abilities of gd T cells have led to a g…