Search results for " African"

Ethnic differences in serum lipoproteins and their determinants in South African women

2010

Genome-Wide Association Studies of the PR Interval in African Americans.

2011

The PR interval on the electrocardiogram reflects atrial and atrioventricular nodal conduction time. The PR interval is heritable, provides important information about arrhythmia risk, and has been suggested to differ among human races. Genome-wide association (GWA) studies have identified common genetic determinants of the PR interval in individuals of European and Asian ancestry, but there is a general paucity of GWA studies in individuals of African ancestry. We performed GWA studies in African American individuals from four cohorts (n = 6,247) to identify genetic variants associated with PR interval duration. Genotyping was performed using the Affymetrix 6.0 microarray. Imputation was p…

Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia

2013

Increased systemic levels of myeloperoxidase (MPO) are associated with the risk of coronary artery disease (CAD). To identify the genetic factors that are associated with circulating MPO levels, we carried out a genome-wide association study (GWAS) and a gene-centric analysis in subjects of European ancestry and African Americans (AAs). A locus on chromosome 1q31.1 containing the complement factor H (CFH) gene was strongly associated with serum MPO levels in 9305 subjects of European ancestry (lead SNP rs800292; P = 4.89 × 10(-41)) and in 1690 AA subjects (rs505102; P = 1.05 × 10(-8)). Gene-centric analyses in 8335 subjects of European ancestry additionally identified two rare M…

Associations between leprosy and serum protein groups

1970

Serum protein group typings were done on a sample of n=173 adult healthy Negroes from the Macua tribe in Mozambique and on n=129 leprous individuals from the same tribe. Unfortunately, the type of leprosy is not known. Whilst between leprosy and haptoglobins, transferrins and Pi proteins no associations could be observed, statistically significant associations between leprosy and ceruloplasmin resp. β2 I were found. It is pointed out that these associations should be confirmed by further research on other populations and with respect to type and process of leprosy, until biological and population genetical interpretations will be possible.

PTCH-1 and MDM2 expression in ameloblastoma from a West African sub-population: implication for chemotherapeutics

2015

INTRODUCTION: ameloblastoma is a slow growing, painless odontogenic swelling which can attain sizes that result in severe deformities of the craniofacial complex. It is the most commonly encountered odontogenic tumor in Nigeria. Surgical intervention is currently the method of treatment; however identification of altered molecular pathways may inform chemotherapeutic potential. The Protein Patched homolog 1 (PTCH-1) is overexpressed in ameloblastoma. Also, mutation in the MDM2 gene can reduce the tumor suppressor function of p53 and promote ameloblastoma growth. No study however has characterized the molecular profile of African cases of ameloblastoma with a view to developing chemotherapeu…

3D geometric morphometric analysis of variation in the human lumbar spine

2019

[Objectives]: The shape of the human lumbar spine is considered to be a consequence of erect posture. In addition, several other factors such as sexual dimorphism and variation in genetic backgrounds also influence lumbar vertebral morphology. Here we use 3D geometric morphometrics (GM) to analyze the 3D morphology of the lumbar spine in different human populations, exploring those potential causes of variation.

Disclosure to God as a Mediator Between Private Prayer and Psychological Well-Being in a Christian Sample.

2021

AbstractAlthough a number of studies have reported the psychological and physical benefits of prayer, only a few have examined the means by which prayer affects health. Winkeljohn Black et al. (J Relig Health 54(2):540–553, 2015. 10.1007/s10943-014-9840-4) found disclosure to God as a mediator in the relationship between prayer and mental health. In their study, the authors used Poloma and Pendleton’s (Rev Relig Res 31(1):46–53, 1989. https://doi.org/10.2307/3511023, ) model of prayer. This study examined whether disclosure to God as a mediator can be upheld with Laird et al.’s (Int J Psychol Relig 14(4):251–272, 2004) prayer model. The study included 285 Polish adults (50.2% of women), age…

Aspetti tipo-cronologici e archeometrici delle ceramiche africane nel territorio di Cignana (Naro, AG, Sicilia)

2020

Il progetto di ricerca, condotto in cotutela tra l'Università di Palermo e Aix-Marseille Université, si basa sullo studio delle ceramiche africane importate in Sicilia tra la fine del I e il VII secolo d.C.. La ricerca si basa sui frammenti - tutte le classi incluse - raccolti dal gruppo di ricerca di Palermo durante le ricognizioni archeologiche nei dintorni della villa romana di Cignana (Agrigento) e nell'entroterra di Termini Imerese (Palermo). L'approccio multidisciplinare archeologico ed archeometrico, condotto in collaborazione con diversi specialisti di queste discipline, ha permesso di definire l'origine delle diverse produzioni e di riflettere sulla loro circolazione in Sicilia, in…

The UN Convention on the Rights of the Child's Role in Litigation Before the Committee of Experts of the African Children's Charter

2020

On the occasion of the 30th anniversary of the UN Convention on the Rights of the Child, this article contributes to a reflection about the Convention's impact on domestic and international case law by investigating its role in, and implications for, litigation before the African Committee of Experts on the Rights and Welfare of the Child. To this end, the analysis starts by tracing the core aspects of the African Charter on the Rights and Welfare of the Child, and by comparing its content to that of the UN Convention. It then investigates the extent to which, in its practice, the African Committee has engaged with (or, indeed, ignored or overlooked) the UN Convention, and critically assess…

Prefazione al romanzo di Jumoke Verissimo, Memoria e desiderio

2021

A well established and renowned poet residing in Canada, Jumoke Verissimo debuted with her first novel, A Small Silence, in 2019. The Preface to the Italian edition elucidates how in Verissimo's fictional account of a dissident intellectual released from prison after the end of Abacha's dictatorship, and in his friendship with a young woman studying at the local University, we find a portrait of today's Nigeria trying to survive its post-independence, post-colonial, post-dictatorship era.